Bernard Fernandez
Commissariat à l'énergie atomique et aux énergies alternatives
16 Papers
143 Citations
Bernard Fernandez is an academic researcher from Commissariat à l'énergie atomique et aux énergies alternatives. The author has contributed to research in topics: Transfer RNA & Pyrococcus abyssi. The author has an hindex of 10, co-authored 15 publications. Previous affiliations of Bernard Fernandez include French Alternative Energies and Atomic Energy Commission.
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Papers
Alliance of proteomics and genomics to unravel the specificities of Sahara bacterium Deinococcus deserti.
Arjan de Groot,Rémi Dulermo,Philippe Ortet,Laurence Blanchard,Philippe J Guerin,Bernard Fernandez,Benoit Vacherie,Carole Dossat,Edmond Jolivet,Patricia Siguier,Michael Chandler,Mohamed Barakat,Alain Dedieu,Valérie Barbe,Thierry Heulin,Suzanne Sommer,Wafa Achouak,Jean Armengaud +17 more
TL;DR: The alliance of proteomics and genomics high-throughput techniques allowed identification of 15 unpredicted genes and reversal of incorrectly predicted orientation of 11 genes, and identification in D. deserti of supplementary genes involved in manganese import.
Proteomic insights into the lifestyle of an environmentally relevant marine bacterium
Joseph Alexander Christie-Oleza,Bernard Fernandez,Balbina Nogales,Rafael Bosch,Jean Armengaud +4 more
TL;DR: High-throughput proteomics is used to define the proteome of Ruegeria pomeroyi DSS-3, a model marine generalist bacterium of the Roseobacter clade, revealing the versatility of the bacterium to adapt to anthropogenic influence, poor nutrient concentrations or the presence of the natural microbial community.
Proteomics-based Refinement of Deinococcus deserti Genome Annotation Reveals an Unwonted Use of Non-canonical Translation Initiation Codons
Mathieu Baudet,Philippe Ortet,Philippe Ortet,Jean-Charles Gaillard,Bernard Fernandez,Philippe J Guerin,Christine Enjalbal,Gilles Subra,Arjan de Groot,Arjan de Groot,Mohamed Barakat,Mohamed Barakat,Alain Dedieu,Jean Armengaud +13 more
TL;DR: The results demonstrate that predicting translation initiation codons is still difficult for some bacteria and that proteomics-based refinement of genome annotations may be helpful in such cases.
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Biosynthesis of Wyosine Derivatives in tRNA: An Ancient and Highly Diverse Pathway in Archaea
Valérie de Crécy-Lagard,Céline Brochier-Armanet,Céline Brochier-Armanet,Jaunius Urbonavičius,Bernard Fernandez,Gabriela Phillips,Benjamin J. Lyons,Akiko Noma,Sophie Alvarez,Louis Droogmans,Jean Armengaud,Henri Grosjean,Henri Grosjean +12 more
TL;DR: Four of the five wybutosine biosynthetic enzymes are ancient and may have been present in the last common ancestor of Archaea and Eucarya and the variations in the distribution pattern of biosynthesis enzymes reflect the diversity of the wyosine derivatives found in different Archaea.
N2-Methylation of Guanosine at Position 10 in tRNA Is Catalyzed by a THUMP Domain-containing, S-Adenosylmethionine-dependent Methyltransferase, Conserved in Archaea and Eukaryota
Jean Armengaud,Jaunius Urbonavičius,Bernard Fernandez,Guylaine Chaussinand,Janusz Marek Bujnicki,Henri Grosjean +5 more
TL;DR: Interestingly, PabTrm-G10 exhibits different domain organization and different catalytic site architecture from another, earlier characterized, tRNA-dimethyltransferase from Pyrococcus furiosus that catalyzes an identical two-step dimethylation of guanosine but at position 26 in tRNAs and is also conserved among all sequenced Eukaryota and Archaea.
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