Benoit Flan
6 Papers
20 Citations
Benoit Flan is an academic researcher. The author has contributed to research in topics: Hepatitis A & Infectivity. The author has an hindex of 4, co-authored 6 publications.
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Papers
Manufacture of plasma-derived products in France and measures to prevent the risk of vCJD transmission: precautionary measures and efficacy of manufacturing processes in prion removal.
Benoit Flan,Samuel Arrabal +1 more
TL;DR: In this paper, a risk analysis approach was initiated by health authorities, based on updated scientific knowledge and precautionary measures were implemented in France and other countries for the management of this new possible risk.
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Hepatitis A: an epidemiological survey in blood donors, France 2015 to 2017.
Pierre Gallian,Valérie Barlet,Lina Mouna,Sylvie Gross,Sophie Lecam,Céline Ricard,Françoise Wind,Elodie Pouchol,Cécile Fabra,Benoit Flan,Catherine Visse,Rachid Djoudi,Elisabeth Couturier,Henriette de Valk,Pierre Tiberghien,Anne-Marie Roque-Afonso +15 more
TL;DR: In France, HAV screening of blood donations in 2017 revealed a HAV-RNA prevalence ca fivefold higher than during 2015–16, and despite a higher male-to-female ratio, only one of 11 infected male donors self-reported being a MSM.
Comparison of nanofiltration efficacy in reducing infectivity of centrifuged versus ultracentrifuged 263K scrapie-infected brain homogenates in "spiked" albumin solutions.
Franco Cardone,Steve Simoneau,Aude Arzel,Maria Puopolo,Vito Angelo Berardi,Hanin Abdel-Haq,Roberta Galeno,Angela De Pascalis,Marco Sbriccoli,Silvia Graziano,Angelina Valanzano,Pierre Porte,Heino Diringer,Paul Brown,Benoit Flan,Maurizio Pocchiari +15 more
TL;DR: The safety of plasma‐derived products is of concern for possible transmission of variant Creutzfeldt‐Jakob disease and proper validation studies based on spiking human plasma or intermediate fractions of plasma fractionation with prions are needed to minimize the risk of transmission.
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Detection and partial discrimination of atypical and classical bovine spongiform encephalopathies in cattle and primates using real-time quaking-induced conversion assay.
Etienne Levavasseur,Anne-Gaëlle Biacabe,Emmanuel Comoy,Audrey Culeux,Katarina Grznarova,Nicolas Privat,Steve Simoneau,Benoit Flan,Véronique Sazdovitch,Danielle Seilhean,Thierry Baron,Stéphane Haïk +11 more
TL;DR: The RT-QuIC assay appears as a practical means for a reliable detection of atypical BSE strains in a homologous or heterologous PrP context.
Persisting higher prevalence of hepatitis A virus RNA in blood donors, France, 2018.
Pierre Gallian,Valérie Barlet,Lina Mouna,Sylvie Gross,Pascal Morel,Sophie Le Cam,Céline Ricard,Claude Maugard,Elodie Pouchol,Benoit Flan,Catherine Visse,Rachid Djoudi,Julie Figoni,Henriette de Valk,Pierre Tiberghien,Anne-Marie Roque-Afonso +15 more
TL;DR: Pierre Gallian1,2, Valérie Barlet2, Sylvie Gross5, Pascal Morel5, Sophie Le Cam6, Céline Ricard7, Claude Maugard8, Elodie Pouchol5, Benoit Flan9, Catherine Visse9, Rachid Djoudi5, Julie Figoni10, Henriette De Valk10, Pierre Tiberghien5,11, AnneMarie Roque-Afonso4 1.
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