Benjamin Brigant
University of Picardie Jules Verne
6 Papers
Benjamin Brigant is an academic researcher from University of Picardie Jules Verne. The author has contributed to research in topics: Kidney disease & Mulibrey nanism. The author has an hindex of 5, co-authored 6 publications. Previous affiliations of Benjamin Brigant include French Institute of Health and Medical Research.
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Papers
Serum levels of miR-126 and miR-223 and outcomes in chronic kidney disease patients.
Ophélie Fourdinier,Eva Schepers,Valérie Metzinger-Le Meuth,Valérie Metzinger-Le Meuth,Griet Glorieux,Sophie Liabeuf,Francis Verbeke,Raymond Vanholder,Benjamin Brigant,Anneleen Pletinck,Momar Diouf,Stéphane Burtey,Gabriel Choukroun,Ziad A. Massy,Laurent Metzinger +14 more
TL;DR: CKD is associated with a decrease in circulatingmiR-223 and miR-126 levels, and the observed link between the two miRNAs’ seric levels and mortality, cardiovascular events or renal events in CKD appears to depend on eGFR.
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Serum microRNAs are altered in various stages of chronic kidney disease: a preliminary study.
Benjamin Brigant,Valérie Metzinger-Le Meuth,Valérie Metzinger-Le Meuth,Ziad A. Massy,Ziad A. Massy,Nathalie McKay,Sophie Liabeuf,M. Pelletier,Marion Sallée,Eléonore M'Baya-Moutoula,Pascale Paul,Tilman B. Drüeke,Stéphane Burtey,Laurent Metzinger +13 more
TL;DR: This exploratory study suggests that specific miRNAs could be biomarkers for complications of CKD, justifying further studies to link changes of miRNA levels with outcomes in CKD patients.
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TRIM37 is highly expressed during mitosis in CHON-002 chondrocytes cell line and is regulated by miR-223
Benjamin Brigant,Yohann Demont,Hakim Ouled-Haddou,Valérie Metzinger-Le Meuth,Sylvie Testelin,Loïc Garçon,Laurent Metzinger,Jacques Rochette +7 more
TL;DR: The results give clues to explain why TRIM37 deficiency in chondrocytes impacts bone growth and suggest that modulating TRIM 37 using miR-223 could be an approach to increase chondrogenesis.
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•Journal Article
miR-92a: A Novel Potential Biomarker of Rapid Aortic Valve Calcification.
Joseph Nader,Valérie Metzinger-Le Meuth,Valérie Metzinger-Le Meuth,Pierre Maitrias,Jean-Régis Humbert,Benjamin Brigant,Christophe Tribouilloy,Laurent Metzinger,Thierry Caus +8 more
TL;DR: In this article, a prospective single-center observational study was conducted on stenotic bicuspid and tricusid human aortic valves to compare the tissular expression of microRNAs.
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TRIMming down to TRIM37: Relevance to Inflammation, Cardiovascular Disorders, and Cancer in MULIBREY Nanism.
TL;DR: It is suggested that normal cells need an optimal equilibrium in TRIM37 expression, and finding a way to keep that balance could lead to potential innovative drugs for MULIBREY nanism, including heart condition and carcinogenesis treatment.