Benedetta D. Chiodini
King's College London
13 Papers
228 Citations
Benedetta D. Chiodini is an academic researcher from King's College London. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 8, co-authored 10 publications. Previous affiliations of Benedetta D. Chiodini include University of Michigan & Mario Negri Institute for Pharmacological Research.
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Papers
Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data
G. Eiriksdottir,T. B. Harris,L. J. Launer,Vilmundur Gudnason,Aaron R. Folsom,Gavin Andrews,C. M. Ballantyne,Nilesh J. Samani,A. S. Hall,P. S. Braund,A. J. Balmforth,Peter H. Whincup,Richard W Morris,Debbie A Lawlor,Gordon D.O. Lowe,Nicholas J. Timpson,Shah Ebrahim,Yoav Ben-Shlomo,George Davey-Smith,Børge G. Nordestgaard,Anne Tybjærg-Hansen,Jeppe Zacho,Matthew A. Brown,Manjinder S. Sandhu,Sally L. Ricketts,Sofie Ashford,Leslie A. Lange,Alexander P. Reiner,Mary Cushman,Russel Tracy,C. Wu,J. Ge,Y. Zou,A. Sun,Joseph Hung,Brendan McQuillan,Peter L. Thompson,John Beilby,Nicole M. Warrington,Lyle J. Palmer,Christoph Wanner,Christiane Drechsler,Michael Hoffmann,F. G. R. Fowkes,Ioanna Tzoulaki,Meena Kumari,Michelle A. Miller,Michael Marmot,Charlotte Onland-Moret,Y. T. van der Schouw,J.M.A. Boer,Cisca Wijmenga,Kay-Tee Khaw,Ramachandran S. Vasan,Renate B. Schnabel,J. F. Yamamoto,E J Benjamin,Heribert Schunkert,Jeanette Erdmann,Inke R. König,Christian Hengstenberg,Benedetta D. Chiodini,MariaGrazia Franzosi,Silvia Pietri,Francesca Gori,Megan E. Rudock,Yongmei Liu,Kurt Lohman,Steve E. Humphries,Anders Hamsten,Paul Norman,Graeme J. Hankey,Konrad Jamrozik,Eric B. Rimm,J. K. Pai,Bruce M. Psaty,Susan R. Heckbert,J. C. Bis,Salim Yusuf,Sonia S. Anand,Engert Jc,C. Xie,Ryan L. Collins,Robert Clarke,David L.H. Bennett,Jaspal S. Kooner,John C. Chambers,Paul Elliott,W. März,Marcus E. Kleber,Bernhard O. Böhm,Winkelmann Br,Olle Melander,Göran Berglund,Wolfgang Koenig,Barbara Thorand,Jens Baumert,Annette Peters,JoAnn E. Manson,J.A. Cooper,P.J. Talmud,Per Ladenvall,Lovisa Johansson,J. H. Jansson,Göran Hallmans,Muredach P. Reilly,Liming Qu,Man Li,Daniel J. Rader,Hugh Watkins,Jemma C. Hopewell,Danish Saleheen,John Danesh,Philippe M. Frossard,Naveed Sattar,Michele Robertson,J. Shepherd,Ernst J. Schaefer,A. Hofman,J. C. M. Witteman,Isabella Kardys,Abbas Dehghan,U de Faire,Anna M. Bennet,Bruna Gigante,Karin Leander,Bas J M Peters,A.H. Maitland-van der Zee,A.H. De Boer,Olaf H. Klungel,Philip Greenland,J. Dai,Simin Liu,Eric J. Brunner,Mika Kivimäki,Denis St. J. O’Reilly,Ian Ford,Chris J. Packard +137 more
- 15 Feb 2011
TL;DR: Human genetic data indicate that C reactive protein concentration itself is unlikely to be even a modest causal factor in coronary heart disease.
Meta-analysis of genome-wide linkage studies in BMI and obesity.
Catherine L. Saunders,Benedetta D. Chiodini,Benedetta D. Chiodini,Pak C. Sham,Cathryn M. Lewis,Victor Abkevich,Adebowale Adeyemo,Mariza de Andrade,Rector Arya,Gerald S. Berenson,John Blangero,Michael Boehnke,Ingrid B. Borecki,Yvon C. Chagnon,Wei Chen,Anthony G. Comuzzie,Hong-Wen Deng,Hong-Wen Deng,Hong-Wen Deng,Ravindranath Duggirala,Mary F. Feitosa,Philippe Froguel,Robert L. Hanson,Johannes Hebebrand,Patricia Huezo-Dias,Ahmed H. Kissebah,Weidong Li,Amy Luke,Lisa J. Martin,M W Nash,Miina Öhman,Miina Öhman,Lyle J. Palmer,Lyle J. Palmer,Leena Peltonen,Leena Peltonen,Markus Perola,R. Arlen Price,Susan Redline,Sathanur R. Srinivasan,Michael P. Stern,Steven Stone,Heather M. Stringham,Stephen T. Turner,Cisca Wijmenga,David A. Collier +45 more
TL;DR: The objective was to provide an overall assessment of genetic linkage data of BMI and BMI‐defined obesity using a nonparametric genome scan meta‐analysis.
APO B gene polymorphisms and coronary artery disease: a meta-analysis
Benedetta D. Chiodini,Simona Barlera,Maria Grazia Franzosi,Violeta Labarta Beceiro,Martino Introna,Gianni Tognoni +5 more
TL;DR: It is suggested that EcoRI and SpIns/Del polymorphisms significantly increase the risk of CAD and MI, and there is a high consistency between small and large studies.
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Meta-Analysis of 4 Coronary Heart Disease Genome-Wide Linkage Studies Confirms a Susceptibility Locus on Chromosome 3q
TL;DR: The strongest evidence for linkage was found on chromosomes 3q26-27 (P = 0.0001) and 2q34-37(P =0.009) as discussed by the authors, weighted by study size confirmed linkage in these regions.
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Bayesian methods for meta-analysis of causal relationships estimated using genetic instrumental variables
Stephen Burgess,Simon G. Thompson,Gavin Andrews,Nilesh J. Samani,Alyson Hall,Peter H. Whincup,Richard W Morris,Debbie A Lawlor,G Davey Smith,Nicholas J. Timpson,Shah Ebrahim,Yoav Ben-Shlomo,Matthew A. Brown,Sally L. Ricketts,M. S. Sandhu,Alexander P. Reiner,Bruce M. Psaty,Leslie A. Lange,Mary Cushman,J. Hung,Peter L. Thompson,John Beilby,Nicole M. Warrington,Lyle J. Palmer,Børge G. Nordestgaard,Anne Tybjærg-Hansen,Jeppe Zacho,C. Wu,G. D. O. Lowe,Ioanna Tzoulaki,Meena Kumari,J. F. Yamamoto,Benedetta D. Chiodini,MariaGrazia Franzosi,Graeme J. Hankey,Konrad Jamrozik,L. Palmer,Eric B. Rimm,J. Pai,Susan R. Heckbert,Joshua C. Bis,Sonia S. Anand,Engert Jc,Rory Collins,Robert Clarke,Olle Melander,Göran Berglund,Per Ladenvall,Lovisa Johansson,J. H. Jansson,Göran Hallmans,Aroon D. Hingorani,Steve E. Humphries,JoAnn E. Manson,Hugh Watkins,Jemma C. Hopewell,Danish Saleheen,R. Frossard,John Danesh,Naveed Sattar,Michele Robertson,James Shepherd,Ernst J. Schaefer,Albert Hofman,Jaqueline C M Witteman,Isabella Kardys,U de Faire,A. Bennet,Ian Ford,Chris J. Packard,Juan P. Casas,Liam Smeeth,Frances Wensley,Jack Bowden,E Di Angelantonio,Pei Gao,Tina Shah,Claudio J. Verzilli,Matthew G. Walker,John C. Whittaker +79 more
TL;DR: A hierarchical model for undertaking a meta‐analysis of multiple studies, in which it is not necessary that the same genetic markers are measured in each study, provides an overall estimate of the causal relationship between the phenotype and the outcome, and an assessment of its heterogeneity across studies.