Ben Krishna
4 Papers
2 Citations
Ben Krishna is an academic researcher. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 2, co-authored 3 publications.
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Papers
Altered TMPRSS2 usage by SARS-CoV-2 Omicron impacts infectivity and fusogenicity
Bo Meng,Adam Abdullahi,Isabella Ferreira,Niluka Goonawardane,Akatsuki Saito,Izumi Kimura,Daichi Yamasoba,P. P. G. Gerber,Saman Fatihi,Surabhi Rathore,Samantha K. Zepeda,Guido Papa,Steven Kemp,Terumasa Ikeda,Mako Toyoda,Toong Seng Tan,Jin Kuramochi,Shigeki Mitsunaga,Takamasa Ueno,Kotaro Shirakawa,Akifumi Takaori-Kondo,Teresa Brevini,Donna L. Mallery,Oscar Charles,Stephen Baker,Gordon Dougan,Christoph Hess,Nathalie Kingston,Paul J. Lehner,Paul A. Lyons,Nick Matheson,Willem H. Ouwehand,Caroline M. Saunders,Charlotte Summers,James Thaventhiran,Mark Toshner,Michael P. Weekes,Patrick Maxwell,Ashley Shaw,Ashlea Bucke,Jo Calder,Laura Canna,Jason Domingo,Anne Elmer,Stewart Fuller,Julie Harris,Sarah Hewitt,Jane Kennet,Sherly Jose,Jenny Kourampa,Anne Meadows,Criona O’Brien,Jane Price,Cherry Publico,Rebecca Rastall,Carla Ribeiro,Jane Rowlands,Valentina Ruffolo,Hugo Tordesillas,Ben Bullman,Benjamin J. Dunmore,Stefan Gräf,Joshua Hodgson,Christopher Huang,K Hunter,Emma Jones,Ekaterina Legchenko,Cecilia Matara,Jennifer M. Martin,Federica Mescia,Ciara O’Donnell,Linda Pointon,Joy Shih,Rachel Sutcliffe,Tobias Tilly,Carmen M. Treacy,Zhen Tong,Jennifer Wood,Marta Wylot,Ariana Betancourt,Georgie Bower,Chiara Cossetti,Aloka De Sa,Maddie Epping,Stuart Fawke,Nicholas Gleadall,Richard Grenfell,Andrew Hinch,Sarah Jackson,Isobel Jarvis,Ben Krishna,Francesca L. Nice,Ommar Omarjee,Marianne Perera,Martin Potts,Nathan Richoz,Veronika Romashova,Luca Stefanucci,Mateusz Strezlecki,Lori Turner,E. D. De Bie,Katherine Bunclark,Masa Josipovic,Michael Mackay,Helen Butcher,Dan Scott Caputo,Matt Chandler,Patrick F. Chinnery,Debbie Clapham-Riley,E Dewhurst,Christian Fernandez,Anita Furlong,Barbara J. Graves,J. Gray,Sabine Hein,Tasmin Ivers,Emma Le Gresley,Rachel Linger,Mary A Kasanicki,Rebecca King,Sara E. Meloy,Alex A. Moulton,Frances E. Muldoon,Nigel R. Ovington,Sofia Papadia,Christopher J. Penkett,Isabel Phelan,Venkatesh-Prasad Ranganath,R. Paraschiv,Abigail Sage,Jennifer G. Sambrook,Ingrid Scholtes,Katherine Schon,Hannah Stark,Kathleen Stirrups,Paul Townsend,Neil Walker,Jennifer Rose Webster,Erika P. Butlertanaka,Yurie Tanaka,Jumpei Ito,Keiya Uriu,Yusuke Kosugi,Mai Suganami,Akiko Oide,Miyabishara Yokoyama,Mika Chiba,Chihiro Motozono,Hesham Nasser,Ryo Shimizu,K. Kitazato,Haruyo Hasebe,Takashi Irie,So Nakagawa,Jiaqi Wu,Miyoko Takahashi,Takasuke Fukuhara,Kenta Shimizu,Kana Tsushima,Haruko Kubo,Yasuhiro Kazuma,Ryosuke Nomura,Yoshihito Horisawa,Kayoko Nagata,Yugo Kawai,Yohei Yanagida,Yusuke Tashiro,Kenzo Tokunaga,Seiya Ozono,Ryoko Kawabata,Nanami Morizako,Kenji Sadamasu,Hiroyuki Asakura,Mami Nagashima,Kazuhisa Yoshimura,Paul Cardenas,E. Muñoz,Veronica Barragan,Sully Márquez,Belén Prado-Vivar,Mónica Becerra-Wong,Mateo Caravajal,Gabriel Trueba,Patricio Rojas-Silva,Michelle Grunauer,Bernardo Gutierrez,Juan José Guadalupe,Juan Carlos Fernandez-Cadena,D. Andrade-Molina,Manuel E. Baldeón,Andrea Pinos,John E. Bowen,Anshu Joshi,Alexandra C. Walls,Laurelle Jackson,Darren Martin,Kenneth G. C. Smith,John S. Bradley,John A. G. Briggs,Jin W. Choi,Elo Madissoon,Kerstin B. Meyer,Petra Mlcochova,Lourdes Ceron-Gutierrez,Rainer Doffinger,Sarah A. Teichmann,Andrew J. Fisher,Matteo Samuele Pizzuto,Anna De Marco,Davide Corti,Myra Hosmillo,Joo-Hyeon Lee,Leo C. James,Lipi Thukral,David Veesler,Alex Sigal,Fotios Sampaziotis,Ian Goodfellow,Kei Sato,Ravindra K. Gupta +219 more
TL;DR: The SARS-CoV-2 Omicron BA.1 variant emerged in 20211 and has multiple mutations in its spike protein this paper , which increased the evasion of therapeutic monoclonal and vaccine-elicited polyclonal neutralizing antibodies after two doses.
Atypical B cells and impaired SARS-CoV-2 neutralisation following booster vaccination in the elderly.
Isabella Ferreira,Chien-Ping Lee,William S. Foster,Adam Abdullahi,Zewen K. Tuong,Benjamin J. Stewart,John R. Ferdinand,Stephane M. Guillaume,Martin Potts,Marianne Perera,Ben Krishna,Ana Paula Alonso,Mia Cabantous,Steven Kemp,Lourdes Ceron-Gutierrez,Soraya Ebrahimi,Paul A. Lyons,Kenneth G. C. Smith,John S. Bradley,Dami A. Collier,Sarah A. Teichmann,Laura E. McCoy,Paul A. MacAry,Rainer Doffinger,Mark R. Wills,Michelle A. Linterman,Menna R. Clatworthy,Ravindra K. Gupta +27 more
TL;DR: The data reveal the extent and potential mechanistic underpinning of the impaired vaccine responses present in the elderly after a booster dose, contributing to their increased susceptibility to COVID-19 infection.
Atypical B cells and impaired SARS-CoV-2 neutralization following heterologous vaccination in the elderly.
Isabella Ferreira,Chien-Ping Lee,William S. Foster,Adam Abdullahi,Lisa M. Dratva,Zewen K. Tuong,Benjamin J. Stewart,John R. Ferdinand,Stephane M. Guillaume,Martin Potts,Marianne Perera,Ben Krishna,Ana Ivis Peñalver,Mia Cabantous,Steven Kemp,Lourdes Ceron-Gutierrez,Soraya Ebrahimi,Paul A. Lyons,Kenneth G. C. Smith,J. Bradley,Dami A. Collier,Laura E. McCoy,Agatha A. van der Klaauw,James Thaventhiran,I. Sadaf Farooqi,Sarah A. Teichmann,Paul A. MacAry,Rainer Doffinger,Mark R. Wills,Michelle A. Linterman,Menna R. Clatworthy +30 more
TL;DR: It is shown that individuals 70 years or older who received a primary two-dose schedule with AZD1222 and booster third dose with mRNA vaccine achieve significantly lower neutralizing antibody responses against SARS-CoV-2 spike pseudotyped virus compared with those younger than 70 at 1 month post booster.
Long COVID: what is known and what gaps need to be addressed.
TL;DR: Long COVID is a chronic condition that follows after acute COVID-19 and is characterized by a wide range of persistent, cyclic symptoms as mentioned in this paper , with a majority of people experiencing at least one symptom (such as cough, fatigue, myalgia, anosmia and dyspnoea) 4 weeks after infection.