Begum Erdogan
Vanderbilt University Medical Center
4 Papers
77 Citations
Begum Erdogan is an academic researcher from Vanderbilt University Medical Center. The author has contributed to research in topics: Gene & Deep sequencing. The author has an hindex of 4, co-authored 4 publications.
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Papers
Diagnostic microRNAs in myelodysplastic syndrome.
Begum Erdogan,Crystal Facey,Julianne Qualtieri,Jason Tedesco,Elizabeth B Rinker,R. Benjamin Isett,John W. Tobias,Donald A. Baldwin,James E. Thompson,James E. Thompson,Martin Carroll,Annette S. Kim,Annette S. Kim,Annette S. Kim +13 more
TL;DR: This study identifies microRNAs (miRNA) and miRNA targets that might represent diagnostic markers for MDS and identified c-Myb and Sufu as potential diagnostic markers of MDS.
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Transfer RNA detection by small RNA deep sequencing and disease association with myelodysplastic syndromes
Yan Guo,Amma Bosompem,Sanjay R. Mohan,Begum Erdogan,Fei Ye,Kasey C. Vickers,Quanhu Sheng,Shilin Zhao,Chung I. Li,Pei Fang Su,Madan Jagasia,Stephen A. Strickland,Elizabeth A. Griffiths,Annette S. Kim,Annette S. Kim +14 more
TL;DR: It is demonstrated that transfer RNA (tRNA) fragments are one of the most common species of small RNA isolated from size selection and that the expression of these species may be useful in the diagnosis of MDS and the prediction of response to therapy.
Methylation of promoters of microRNAs and their host genes in myelodysplastic syndromes
Begum Erdogan,Amma Bosompem,Dunfa Peng,Leng Han,Emily A. Smith,Mija E. Kennedy,Catherine E. Alford,Huiyun Wu,Zhongming Zhao,Claudio A. Mosse,Wael El-Rifai,Annette S. Kim +11 more
TL;DR: It is demonstrated that these miRNAs are predominantly intragenic, and that, in many cases, they and their host genes are expressed in a similar pattern during myeloid maturation, suggesting their co-regulation.
Differential expression of ribosomal proteins in myelodysplastic syndromes.
Elizabeth B Rinker,Julie C. Dueber,Julianne Qualtieri,Jason Tedesco,Begum Erdogan,Amma Bosompem,Annette S. Kim +6 more
TL;DR: There is overexpression of RPS24, DKC1 and SBDS in MDS, in contrast to the haploinsufficiency identified in the congenital bone marrow failure syndromes and in acquired 5q minus MDS.
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