Bas R. Leeflang
Utrecht University
42 Papers
854 Citations
Bas R. Leeflang is an academic researcher from Utrecht University. The author has contributed to research in topics: Nuclear magnetic resonance spectroscopy & Proton NMR. The author has an hindex of 24, co-authored 42 publications. Previous affiliations of Bas R. Leeflang include Kobe Pharmaceutical University & University of Rome Tor Vergata.
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Papers
Oxygenated metabolites of anandamide and 2-arachidonoylglycerol : conformational analysis and interaction with cannabinoid receptors, membrane transporter, and fatty acid amide hydrolase
Mario van der Stelt,J. Albert van Kuik,Monica Bari,Guus van Zadelhoff,Bas R. Leeflang,Gerrit A. Veldink,Alessandro Finazzi-Agrò,Johannes F.G. Vliegenthart,Mauro Maccarrone +8 more
TL;DR: Analysis of (1)H NMR spectra revealed that chloroform did not induce notably different conformations in the acyl chain of 15(S)-hydroxy-eicosa-5Z,8Z,11Z,13E-tetraenoic acid as compared with water.
Structural characterisation of the exopolysaccharide produced by Lactobacillus delbrückii subspecies bulgaricus rr grown in skimmed milk.
TL;DR: The exopolysaccharide of Lactobacillus delbrückii subsp.
150
Development of a 1H NMR structural-reporter-group concept for the primary structural characterisation of α-D-glucans
TL;DR: An NMR study of proton chemical shift patterns of known linear alpha-D-glucopyranose di- and trisaccharide structures was carried out, and a 1H NMR structural-reporter-group concept was formulated to function as a tool in the structural analysis of alpha- D- glucans.
117
A 1H-NMR and MD study of intramolecular hydrogen bonds in methyl β-cellobioside
Bas R. Leeflang,Johannes F.G. Vliegenthart,Loes M. J. Kroon-Batenburg,Bouke P. van Eijck,Jan Kroon +4 more
TL;DR: In this paper, the existence of an HO-3⋯O-5′ intramolecular hydrogen bond in methyl β-cellobioside in solution in Me 2 SO-d 6 and H 2 O-CD 3 OD (4:1 w/w) was studied by 500-MHz 1 H-NMR spectroscopy and MD simulations.
109
The Giardia intestinalis filamentous cyst wall contains a novel β(1-3)-N-acetyl-d-galactosamine polymer: a structural and conformational study
Gerrit J. Gerwig,J. Albert van Kuik,Bas R. Leeflang,Johannis P. Kamerling,Johannes F.G. Vliegenthart,Craig D. Karr,Edward L. Jarroll +6 more
TL;DR: The highly insoluble nature of the Giardia cyst wall must be due to these strong interchain interactions and, probably, a strong association between the carbohydrate and the protein moiety.