13 Papers
7 Citations
Bas Muilwijk is an academic researcher from Netherlands Organisation for Applied Scientific Research. The author has contributed to research in topics: Metabolome & Metabolomics. The author has an hindex of 10, co-authored 13 publications.
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Papers
Microbial metabolomics with gas chromatography/mass spectrometry
TL;DR: An analytical method for the analysis of microbial metabolomes, consisting of an oximation and silylation derivatization reaction and subsequent analysis by gas chromatography coupled to mass spectrometry, was presented in this paper.
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Microbial metabolomics: toward a platform with full metabolome coverage.
TL;DR: A strategy for the development of an advanced analytical platform that allows the comprehensive analysis of microbial metabolomes and its application to the analysis of the metabolome composition of mid-logarithmic E. coli cells grown on a mineral salts medium using glucose as the carbon source is presented.
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Metabolomics of cerebrospinal fluid reveals changes in the central nervous system metabolism in a rat model of multiple sclerosis
Marek J. Noga,Adrie Dane,Shanna Shi,Amos Attali,Hans van Aken,Ernst Suidgeest,Tinka Tuinstra,Bas Muilwijk,Leon Coulier,Theo M. Luider,Theo H. Reijmers,Rob J. Vreeken,Thomas Hankemeier +12 more
TL;DR: CSF metabolomics in an acute EAE rat model was investigated using targetted LC–MS and GC–MS, suggesting significant changes in CNS metabolism over the course of MBP-induced neuro inflammation.
Identifying inhibitory compounds in lignocellulosic biomass hydrolysates using an exometabolomics approach
Ying Zha,Johan A. Westerhuis,Bas Muilwijk,Karin M. Overkamp,Bernadien M Nijmeijer,Leon Coulier,Age K. Smilde,Peter J. Punt +7 more
TL;DR: Inhibitory compounds in lignocellulosic biomass hydrolysates were successfully identified using a non-targeted systematic approach: metabolomics.
The Impact of Delayed Storage on the Measured Proteome and Metabolome of Human Cerebrospinal Fluid
Therese Rosenling,Marcel P. Stoop,Agnieszka Smolinska,Bas Muilwijk,Leon Coulier,Shanna Shi,Adrie Dane,Christin Christin,Frank Suits,Peter Horvatovich,Sybren S. Wijmenga,Lutgarde M. C. Buydens,Rob J. Vreeken,Thomas Hankemeier,Alain J. van Gool,Theo M. Luider,Rainer Bischoff +16 more
TL;DR: The measured proteome and metabolome of centrifuged human CSF is stable at room temperature for up to 2 hours, which gives laboratory personnel at the collection site sufficient time to aliquot samples before freezing and storage at -80 °C.
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