Bartley D. Mitchell
Harvard University
7 Papers
51 Citations
Bartley D. Mitchell is an academic researcher from Harvard University. The author has contributed to research in topics: Neurogenesis & Neural stem cell. The author has an hindex of 6, co-authored 7 publications.
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Papers
Adult neurogenesis and repair of the adult CNS with neural progenitors, precursors, and stem cells.
TL;DR: A discussion of what the function might be of newly generated neurons in the adult brain and a summary of current thinking about the consequences of disturbed adult neurogenesis and the reaction of neurogenic regions to disease are provided.
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Constitutive and Induced Neurogenesis in the Adult Mammalian Brain: Manipulation of Endogenous Precursors toward CNS Repair
TL;DR: Elucidation of the relevant molecular controls may both allow control over transplanted precursor cells and potentially allow the development of neuronal replacement therapies for neurodegenerative disease and other CNS injuries that do not require transplantation of exogenous cells.
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Large-scale maintenance of dual projections by callosal and frontal cortical projection neurons in adult mice
TL;DR: It is found that there is widespread overlap in populations of long‐distance projection neurons in mice; many projection neurons have simultaneous projections to both contralateral somatosensory cortex and ipsilateral frontal cortex, and a considerable number of these dual projections persist into adulthood.
The repair of complex neuronal circuitry by transplanted and endogenous precursors.
TL;DR: Elucidation of the relevant molecular controls may both allow control over transplanted precursor cells and potentially allow for the development of neuronal replacement therapies for neurodegenerative disease and other CNS injuries that might not require transplantation of exogenous cells.
Neural Stem Cells
U.S. Sohur,Jason G. Emsley,Bartley D. Mitchell,Jeffrey D. Macklis +3 more
- 01 Jan 2007
TL;DR: Current knowledge about constitutive adult mammalian neurogenesis is reviewed, the critical differences between neurogenic and nonneurogenic regions in the adult brain are highlighted, and the cardinal features of two well-described neurogenic regions are described.