Bart Staels
Pasteur Institute
9 Papers
8 Citations
Bart Staels is an academic researcher from Pasteur Institute. The author has contributed to research in topics: Medicine & Steatosis. The author has an hindex of 5, co-authored 9 publications. Previous affiliations of Bart Staels include university of lille.
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Papers
PPARs in liver physiology.
TL;DR: An overview of the latest advances in the study of PPARs in liver physiology, with a specific focus on formerly neglected aspects, such as tissular zonation, cellular heterogeneity, circadian rhythms, sexual dimorphism and species-specific features, can be found in this paper.
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Hepatic Molecular Signatures Highlight the Sexual Dimorphism of Nonalcoholic Steatohepatitis (NASH)
Jimmy Vandel,Julie Dubois-Chevalier,Céline Gheeraert,Bruno Derudas,V. Raverdy,Dorothée Thuillier,Luc Van Gaal,Sven Francque,François Pattou,Bart Staels,Jérôme Eeckhoute,Philippe Lefebvre +11 more
TL;DR: The limited availability of representative NASH cohorts with associated liver biopsies, the gold standard for NASH diagnosis, probably explains the poor overlap between published “omics”‐defined NASH signatures.
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NASH-related increases in plasma bile acid levels depend on insulin resistance.
Guillaume Grzych,Oscar Chávez-Talavera,Amandine Descat,Dorothée Thuillier,An Verrijken,Mostafa Kouach,Vanessa Legry,Hélène Verkindt,Violeta Raverdy,Benjamin Legendre,R. Caiazzo,Luc Van Gaal,Jean-François Goossens,Réjane Paumelle,Sven Francque,François Pattou,Joel T. Haas,Anne Tailleux,Bart Staels +18 more
- 01 Apr 2021
TL;DR: It is found that plasma bile acids are only elevated in patients with NASH when significant insulin resistance is present, limiting their utility as NASH markers.
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Deletion of fibroblast activation protein provides atheroprotection.
Sokrates Stein,Julien Weber,Stefanie Nusser-Stein,Jürgen Pahla,Hui Emma Zhang,Shafeeq A. Mohammed,Sara Oppi,Daniel S. Gaul,Francesco Paneni,Anne Tailleux,Bart Staels,Ferdinand von Meyenn,Frank Ruschitzka,Mark D. Gorrell,Thomas F. Lüscher,Christian M. Matter +15 more
TL;DR: In this article, the effects of constitutive FAP deletion on plaque formation in atherosclerosis-prone apolipoprotein E (Apoe) or low-density lipoprotein receptor (Ldlr) knockout mice were investigated.
Human Aortic Valve Interstitial Cells Display Proangiogenic Properties During Calcific Aortic Valve Disease.
Nicolas Gendron,Mickael Rosa,Adeline Blandinières,Yoann Sottejeau,Elisa Rossi,Eric Van Belle,Salim Idelcadi,Séverine Lecourt,André Vincentelli,Audrey Cras,R. Jashari,Richard Chocron,Yaël Baudouin,Thibault Pamart,Ivan Bièche,Nathalie Nevo,Bernard Cholley,Jeanne Rancic,Bart Staels,Pascale Gaussem,Annabelle Dupont,Alain Carpentier,Sophie Susen,David M. Smadja +23 more
TL;DR: The first proof of an angiogenic potential of human VICs isolated from patients with calcific aortic valve disease is provided, with a perivascular differentiation ability and a VEGF-A paracrine effect.
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