Bart De Corte
Janssen Pharmaceutica
29 Papers
650 Citations
Bart De Corte is an academic researcher from Janssen Pharmaceutica. The author has contributed to research in topics: Aryl & Alkyl. The author has an hindex of 13, co-authored 29 publications. Previous affiliations of Bart De Corte include Ghent University & Center for Advanced Biotechnology and Medicine.
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Papers
Evolution of Anti-HIV Drug CandidatesPart 2: Diaryltriazine (DATA) Analogues
Donald William Ludovici,Robert W. Kavash,Michael J. Kukla,Chih Y. Ho,Hong Ye,Bart De Corte,Koen Andries,Marie-Pierre de Béthune,Hilde Azijn,Rudi Pauwels,Henry E.L. Moereels,Jan Heeres,Lucien Maria Henricus Koymans,Marc René De Jonge,Koen Jeanne Alfons Van Aken,Frederik Frans Desire Daeyaert,Paul J. Lewi,Kalyan Das,Edward Arnold,Paul Adriaan Jan Janssen +19 more
TL;DR: A synthesis program directed toward improving the stability of imidoyl thiourea based non-nucleoside reverse transcriptase inhibitors led to the discovery of diaryltriazines (DATAs), a new class of potent NNRTIs.
137
Patent
Hiv replication inhibiting pyrimidines
Bart De Corte,Marc René De Jonge,Jan Heeres,Chih Yung Ho,Paul A. J. Janssen,Robert W. Kavash,Lucien Maria Henricus Koymans,Michael J. Kukla,Donald William Ludovici,Koen Jeanne Alfons Van Aken +9 more
- 01 Nov 1999
TL;DR: In this article, the use of compounds of formula (I), the Noxides, the pharmaceutically acceptable addition salts, quaternary amines and the stereochemically isomeric forms thereof was discussed.
114
Patent
HIV inhibiting pyrimidine derivatives
Koenraad Jozef Lodewijk Marcel Andries,Bart De Corte,Marc René De Jonge,Jan Heeres,Chih Yung Ho,Marcel August Constant Janssen,Paul A. J. Janssen,Lucien Maria Henricus Koymans,Michael J. Kukla,Donald William Ludovici,Koen Jeanne Alfons Van Aken +10 more
- 24 Mar 1999
TL;DR: In this article, the use of the Noxides, the pharmaceutically acceptable addition salts and the stereochemically isomeric forms thereof, was discussed, and new compounds being a subgroup of the compounds of formula (I).
113
Patent
HIV replication inhibitors
Michael J. Kukla,Donald William Ludovici,Robert W. Kavash,Bart De Corte,Jan Heeres,Paul A. J. Janssen,Lucien Maria Henricus Koymans,Marc René De Jonge,Koen Jeanne Alfons Van Aken,Alain Krief,Ruben Gerardus George Leenders +10 more
- 03 May 2001
TL;DR: In this paper, the Noxides, the pharmaceutically acceptable addition salts, the quaternary amines and the stereochemically isomeric forms thereof, provided that when Q is halo then Z is N; or when X is polyhaloC1-6alkyl then Y is hydrogen or C1- 6alkyl; their use as a medicine, their processes for preparation and pharmaceutical compositions comprising them.
55
Patent
Prodrugs of HIV replication inhibiting pyrimidines
Kukla Michael Joseph,Donald William Ludovici,Kavash Robert W,Bart De Corte,Jan Heeres,Paul Adriaan Jan Janssen,Lucien Maria Henricus Koymans,Jonge Marc Rene De,Aken Koen Jeanne Alfons Van,Alain Krief +9 more
- 03 May 2001
TL;DR: In this article, the authors present compounds of the formula (I): (A1)(A2)N-R1, the Noxide forms, the pharmaceutically acceptable addition salts, the quaternary amines and stereochemically isomeric forms thereof.
48