Barry McCarthy
New York Stem Cell Foundation
4 Papers
2 Citations
Barry McCarthy is an academic researcher from New York Stem Cell Foundation. The author has contributed to research in topics: Medicine & Gene. The author has co-authored 1 publications.
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Papers
Modeling gene × environment interactions in PTSD using human neurons reveals diagnosis-specific glucocorticoid-induced gene expression
Carina Seah,Michael S. Breen,Tomasz Rusielewicz,Heather N. Bader,Changxin Xu,Christopher J. Hunter,Barry McCarthy,P. M. Deans,Mitali Chattopadhyay,Jordan Goldberg,Frank Desarnaud,Iouri Makotkine,Janine D. Flory,Linda M. Bierer,Migle Staniskyte,Lauren Bauer,Katie Brenner,Geoff Buckley-Herd,Sean DesMarteau,Patrick Fenton,Peter Ferrarotto,Jenna Hall,Selwyn Jacob,Travis Kroeker,Gregory Lallos,H. Martínez,Paull McCoy,Frederick J. Monsma,Dorota Moroziewicz,Reid Otto,Kathryn S. Reggio,Bruce Sun,Rebecca Tibbets,Dong-Woo Shin,Hongyan Zhou,Matthew Zimmer,Scott Noggle,Laura M. Huckins,Daniel Paull,Kristen J. Brennand,Rachel Yehuda +40 more
TL;DR: This article found evidence of a coregulated network of transcription factors that mediates glucocorticoid hyper-responsivity in post-traumatic stress disorder (PTSD) using human induced pluripotent stem cell (hiPSC)-derived glutamatergic neurons and peripheral blood mononuclear cells (PBMCs).
An assessment of the impact of Raman based glucose feedback control on CHO cell bioreactor process development.
Luke Gibbons,Francis Maslanka,Nikky Le,Joseph K. McLaughlin,Fiona Madden,Ronan Hayes,Barry McCarthy,Christopher Rode,Jim O'Mahony,Rosemary Rea,Caitlin O’Mahony-Hartnett +10 more
TL;DR: In this article , the impact of Raman based feedback control on early and late phase development bioreactors by using a Raman-based PLS model and PAT management system to control glucose in two CHO cell line bioreactor processes was assessed.
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Common genetic variation impacts stress response in the brain
Carina Seah,Rebecca Signer,Michael Deans,Heather N. Bader,Tom Rusielewicz,Emily M. Hicks,Hannah Young,Alanna C. Cote,Kayla Townsley,Changxin Xu,Christopher J. Hunter,Barry McCarthy,Jordan Goldberg,Saunil Dobariya,Paul E. Holtzherimer,Keith A. Young,Scott Noggle,J. H. Krystal,Daniel Paull,Matthew J. Girgenti,Rachel Yehuda,Kristen J. Brennand,L. M. Huckins +22 more
TL;DR: Molecular stress-encoding explains individualized responses to traumatic stress; incorporating trauma into genomic studies of brain disorders is likely to improve diagnosis, prognosis, and drug discovery.
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Modeling gene x environment interactions in PTSD using glucocorticoid-induced transcriptomics in human neurons
Michael S. Breen,Tom Rusielewicz,Heather N. Bader,Heather N. Bader,Carina Seah,Changxin Xu,Changxin Xu,Christopher J. Hunter,Barry McCarthy,Mitali Chattopadhyay,Mitali Chattopadhyay,Frank Desarnaud,Frank Desarnaud,Iouri Makotkine,Iouri Makotkine,Janine D. Flory,Janine D. Flory,Linda M. Bierer,Linda M. Bierer,Migle Staniskyte,Migle Staniskyte,Nyscf Global Array Team,Scott Noggle,Daniel Paull,Kristen J. Brennand,Rachel Yehuda,Rachel Yehuda +26 more
TL;DR: This paper assessed the impact of genomic differences following glucocorticoid administration by examining the transcriptional profile of human induced pluripotent stem cell (hiPSC)-derived glutamatergic neurons and live cultured peripheral blood mononuclear cells from combat veterans with PTSD and without PTSD.
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