Barbara J. Sahakian
University of Cambridge
657 Papers
5.6K Citations
Barbara J. Sahakian is an academic researcher from University of Cambridge. The author has contributed to research in topics: Cognition & Medicine. The author has an hindex of 145, co-authored 612 publications. Previous affiliations of Barbara J. Sahakian include University of Westminster & Shanghai Jiao Tong University.
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Papers
Characteristic neurocognitive profile associated with adult attention-deficit/hyperactivity disorder.
A McLean,Jonathan H. Dowson,Brian Toone,Susan Young,E. Bazanis,Trevor W. Robbins,Barbara J. Sahakian +6 more
TL;DR: The demonstration of neuropsychological dysfunction in the adult ADHD cohort provides some support for the validity of this diagnosis in adulthood and there is broad consistency between the cognitive profile revealed in the current investigation and that previously demonstrated in a study of medication-naïve ADHD children.
Neuroethics and public engagement training needed for neuroscientists.
TL;DR: The authors are funded in part by Wellcome Trust Programme Grant (076274/Z/04/Z) to B.J.S., Trevor Robbins, Barry Everitt and Angela Roberts.
Serotonin depletion amplifies distinct human social emotions as a function of individual differences in personality
Jonathan W. Kanen,Frederique E. Arntz,Frederique E. Arntz,Robyn Yellowlees,Robyn Yellowlees,Rudolf N. Cardinal,Annabel Price,David M Christmas,Annemieke M. Apergis-Schoute,Annemieke M. Apergis-Schoute,Barbara J. Sahakian,Trevor W. Robbins +11 more
TL;DR: The findings show how individual differences in personality, when combined with fluctuations of serotonin, may produce diverse emotional phenotypes, which has implications for understanding vulnerability to psychopathology, determining who may be more sensitive to serotonin-modulating treatments, and casts new light on the functions of serotonin in emotional processing.
Lack of effects of guanfacine on executive and memory functions in healthy male volunteers
Ulrich Müller,Luke Clark,Minh L. Lam,Rebecca M. Moore,C. Louise Murphy,Nicola K. Richmond,Ranbir S. Sandhu,Ingrid A. Wilkins,David K. Menon,Barbara J. Sahakian,Trevor W. Robbins +10 more
TL;DR: Negative effects on blood pressure and trend effects on digit span backward and go reaction time indicate a mild sedative effect of guanfacine at these doses, possibly via mechanisms of autoreceptor down-regulation.
Psychometric Properties and Validation of the EMOTICOM Test Battery in a Healthy Danish Population.
Vibeke H. Dam,Christa K Thystrup,Peter S Jensen,Amy R. Bland,Erik Lykke Mortensen,Rebecca Elliott,Barbara J. Sahakian,Gitte M. Knudsen,Vibe G. Frokjaer,Dea S. Stenbæk +9 more
TL;DR: Overall, many of the EMOTICOM tasks were found to be useful and objective measures of hot cognition although select tasks may benefit from modifications to avoid floor and ceiling effects in healthy individuals.