Barbara Eckel
Technische Universität München
12 Papers
85 Citations
Barbara Eckel is an academic researcher from Technische Universität München. The author has contributed to research in topics: Amyloid precursor protein & Isoflurane. The author has an hindex of 7, co-authored 12 publications. Previous affiliations of Barbara Eckel include Ludwig Maximilian University of Munich.
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Papers
The impact of cardiopulmonary bypass on systemic interleukin-6 release, cerebral nuclear factor-kappa B expression, and neurocognitive outcome in rats.
Bettina Jungwirth,Barbara Eckel,Manfred Blobner,Kristine Kellermann,Eberhard Kochs,G. Burkhard Mackensen +5 more
TL;DR: Pronounced systemic inflammatory responses to experimental CPB associated with increased hippocampal expression of NF-&kgr;B were not accompanied by neurocognitive impairment, which suggests that other factors beyond CPB and inflammatory responses might contribute to adverse neuroc cognitive outcomes after cardiac surgery.
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Effects of sevoflurane on cognitive deficit, motor function, and histopathology after cerebral ischemia in rats.
Eva Eberspächer,Barbara Eckel,Kristin Engelhard,K. Müller,William E. Hoffman,Manfred Blobner,Christian Werner +6 more
TL;DR: Cognitive and behavioral function as well as hippocampal damage in rats subjected to cerebral ischemia under sevoflurane compared with fentanyl/nitrous oxide (N2O)/O2 anesthesia are evaluated.
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Transgenic Alzheimer mice have a larger minimum alveolar anesthetic concentration of isoflurane than their nontransgenic littermates.
TL;DR: The increased MAC value in aged heterozygote APP23 mice seems to be attributable to changes related to Alzheimer's disease.
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Effects of isoflurane-induced anaesthesia on cognitive performance in a mouse model of Alzheimer's disease: A randomised trial in transgenic APP23 mice.
Barbara Eckel,Frauke Ohl,Laura Starker,Gerhard Rammes,Ralph Bogdanski,Eberhard Kochs,Manfred Blobner +6 more
TL;DR: Isoflurane may have protective, rather than detrimental, effects on cognition in Alzheimer's disease.
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Cognitive deficits after systemic induction of inducible nitric oxide synthase: a randomised trial in rats.
TL;DR: Early, reversible cognitive deficits are demonstrated in a rat model of systemic inflammation with increased systemic iNOS activity, as systemic inhibition of iN OS activity prevented rats from the deficit in short-term memory.
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