Baptiste Hamelin
University Hospital of Basel
6 Papers
Baptiste Hamelin is an academic researcher from University Hospital of Basel. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 1, co-authored 1 publications.
Chat about Author
Papers
Glucocorticoids promote breast cancer metastasis.
Milan M. S. Obradović,Milan M. S. Obradović,Baptiste Hamelin,Nenad Manevski,Joana Pinto Couto,Joana Pinto Couto,Joana Pinto Couto,Atul Sethi,Atul Sethi,Atul Sethi,Marie-May Coissieux,Marie-May Coissieux,Simone Münst,Ryoko Okamoto,Ryoko Okamoto,Hubertus Kohler,Alexander Schmidt,Mohamed Bentires-Alj,Mohamed Bentires-Alj +18 more
TL;DR: The results indicate that the activation of the glucocorticoid receptor increases heterogeneity and metastasis, which suggests that caution is needed when using glucOCorticoids to treat patients with breast cancer who have developed cancer-related complications.
PI3K inhibition circumvents resistance to SHP2 blockade in metastatic triple-negative breast cancer
Romain J. Amante,Charly Jehanno,Duvini De Silva,Marie-May Coissieux,Markus Ackerknecht,Vincent Romanet,Atul Sethi,Baptiste Hamelin,Bogdan-Tiberius Preca,Salvatore Piscuoglio,Charlotte K.Y. Ng,Morvarid Mohseni,Mohamed Bentires-Alj +12 more
TL;DR: In this article , the effect of targeting PI3K and SHP2 alone or in combination in preclinical models of metastatic triple-negative breast cancer (TNBC) was evaluated.
4
Single-cell analysis reveals inter- and intratumour heterogeneity in metastatic breast cancer
Baptiste Hamelin,Milan M. S. Obradović,Atul Sethi,Michal Kloc,Simone Muenst,Christian Beisel,Katja Eschbach,Hubertus Kohler,Savas D. Soysal,Marcus Vetter,Walter P. Weber,Michael B. Stadler,Mohamed Bentires-Alj +12 more
TL;DR: The authors performed single-cell RNA-Seq on tumours and matched lung macrometastases of patient-derived xenografts of breast cancer patients to identify molecular mechanisms of metastasis during colonization, one of the most important yet poorly understood steps of the cascade.
1
Bone marrow haematopoiesis in patients with COVID-19.
Ewerton Marques-Maggio,Umberto Maccio,Serena Galli,Nathalie Schwab,Angela Frank,Baptiste Hamelin,Zsuzsanna Varga,César Nombela-Arrieta,Kirsten D. Mertz,Alexandre Theocharides,Viktor H. Koelzer +10 more
TL;DR: In this article , the authors performed an in-depth analysis of the impact of severe coronavirus disease 2019 (COVID-19) on bone marrow haematopoiesis in correlation with clinical and laboratory parameters.
Nicotinamide N‐methyltransferase sustains a core epigenetic program that promotes metastatic colonization in breast cancer
Joana Pinto Couto,Milica Vulin,Charly Jehanno,Marie-May Coissieux,Baptiste Hamelin,Alexander Schmidt,Robert Ivanek,Atul Sethi,Konstantin Bräutigam,Anja Frei,Carolina Hager,Madhuri Manivannan,Jorge Gomez-Miragaya,Milan M. S. Obradović,Zsuzsanna Varga,Viktor H. Koelzer,Kirsten D. Mertz,Mohamed Bentires-Alj +17 more
TL;DR: In this paper , the authors reveal a critical activity of the NNMT−PRDM5−COL1A1 axis for cancer cell plasticity and metastasis in basal-like breast cancer.