Baixing Wu
Fudan University
31 Papers
78 Citations
Baixing Wu is an academic researcher from Fudan University. The author has contributed to research in topics: RNA & Gene. The author has an hindex of 13, co-authored 20 publications. Previous affiliations of Baixing Wu include Southern University of Science and Technology.
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Papers
RNA 5-Methylcytosine Facilitates the Maternal-to-Zygotic Transition by Preventing Maternal mRNA Decay.
Ying Yang,Lu Wang,Xiao Han,Wen-Lan Yang,Wen-Lan Yang,Mengmeng Zhang,Hai-Li Ma,Bao-Fa Sun,Ang Li,Ang Li,Jun Xia,Jing Chen,Jing Chen,Jian Heng,Baixing Wu,Yu-Sheng Chen,Yu-Sheng Chen,Jia-Wei Xu,Xin Yang,Xin Yang,Huan Yao,Huan Yao,Jiawei Sun,Cong Lyu,Hailin Wang,Ying Huang,Ying-Pu Sun,Yongliang Zhao,Anming Meng,Jinbiao Ma,Feng Liu,Yun-Gui Yang +31 more
TL;DR: This study discovered that Y-box binding protein 1 (Ybx1) preferentially recognizes m5C-modified mRNAs through π-π interactions with a key residue, Trp45, in YbX1's cold shock domain (CSD), which plays essential roles in maternal mRNA stability and early embryogenesis of zebrafish.
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Molecular basis for the specific and multivariant recognitions of RNA substrates by human hnRNP A2/B1.
TL;DR: In this paper, the crystal structures of tandem RRM domains of hnRNP A2/B1 in complex with various RNA substrates, elucidating specific recognitions of AGG and UAG motifs by RRM1 and RRM2 domains, respectively.
CPSF30-L-mediated recognition of mRNA m6A modification controls alternative polyadenylation of nitrate signaling-related gene transcripts in Arabidopsis.
Yifeng Hou,Jing Sun,Baixing Wu,Gao Yangyang,Hongbo Nie,Zhentian Nie,Shuxuan Quan,Wang Yong,Xiaofeng Cao,Sisi Li +9 more
TL;DR: It is demonstrated that m 6A modification regulates APA in Arabidopsis, and revealed that m6A reader CPSF30-L affects nitrate signaling by controlling APA.
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Readers, writers and erasers of N6-methylated adenosine modification
TL;DR: Overall, this review aims to mechanistically explain the reversible and dynamic nature of this unique RNA internal modification that contributes to the complexity of RNA-mediated gene regulation, and inspire new studies in epitranscriptomics.
102
Hypoxia induces mitochondrial protein lactylation to limit oxidative phosphorylation
Yun-Zi Mao,Jiaojiao Zhang,Qian Zhou,Xiadi He,Zhifang Zheng,Yun Wei,Kaiqiang Zhou,Yan Lin,Haowen Yu,Haihui Zhang,Yineng Zhou,Pengcheng Lin,Baixing Wu,Yi-Yuan Yuan,Jian-Yuan Zhao,Wei Xu,Shimin Zhao +16 more
TL;DR: It is reported that mitochondrial protein lactylation is induced by intracellular hypoxia to constrain OXPHOS, and it is revealed that mitochondrial protein lactylation integrates intracellular hypoxia and lactate signals to regulate OXPHOS.
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