B. Ostretsov
University of Haifa
4 Papers
5 Citations
B. Ostretsov is an academic researcher from University of Haifa. The author has contributed to research in topics: Proinflammatory cytokine & Inflammation. The author has an hindex of 1, co-authored 4 publications.
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Papers
Estrogen-related receptor agonism reverses mitochondrial dysfunction and inflammation in the aging kidney
Xiaoxin X. Wang,Komuraiah Myakala,Andrew E. Libby,Julia Panov,Suman Ranjit,Shogo Takahashi,Shogo Takahashi,Bryce A. Jones,Kanchan Bhasin,Yue Qi,Kristopher W. Krausz,Patricia M. Zerfas,Thomas J. Velenosi,Daxesh P. Patel,Parnaz Daneshpajouhnejad,Avi Titievsky,Vadim V. Sharov,B. Ostretsov,Cyrielle Billon,Arindam Chatterjee,John K. Walker,Jeffrey B. Kopp,Avi Z. Rosenberg,Frank J. Gonzalez,Udayan Guha,Leonid Brodsky,Thomas P. Burris,Moshe Levi +27 more
TL;DR: In this paper, the role of the nuclear hormone receptors, the estrogen-related receptors (ERRs) in regulation of age-related mitochondrial dysfunction and inflammation was investigated in 21-month-old mice.
Adaptation of the pine fungal pathogen Grosmannia clavigera to monoterpenes: Biochemical mechanisms revealed by RNA-seq analysis
TL;DR: Overall, this study identified gene expression regulations supported by two data sets as well as new putative transcripts related to new processes that might be important for G. clavigera tolerance to terpenes.
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ERR agonism reverses mitochondrial dysfunction and inflammation in the aging kidney
Xiaoxin X. Wang,Shogo Takahashi,Andrew E. Libby,Komuraiah Myakala,Bryce A. Jones,Kanchan Bhasin,Yue Qi,Kristopher W. Krausz,Patricia M. Zerfas,Julia Panov,Thomas J. Velenosi,Daxesh P. Patel,Parnaz Daneshpajouhnejad,Brandon Ginley,Pinaki Sarder,Avi Titievsky,Vadim V. Sharov,B. Ostretsov,Jeffrey B. Kopp,Avi Z. Rosenberg,Frank J. Gonzalez,Udayan Guha,Leonid Brodsky,Thomas P. Burris,Moshe Levi +24 more
TL;DR: In this paper, the role of the nuclear hormone receptors, the estrogen related receptors (ERRs) in regulation of age-related mitochondrial dysfunction and inflammation was studied in mice with lifelong caloric restriction.
ERR agonism reverses mitochondrial dysfunction and inflammation in aging
Xiaoxin X. Wang,Shogo Takahashi,Andrew E. Libby,Komuraiah Myakala,Bryce A. Jones,Kanchan Bhasin,Yunpeng Qi,Kristopher W. Krausz,Patricia M. Zerfas,Julia Panov,Thomas J. Velenosi,Daxeshkumar P. Patel,Parnaz Daneshpajouhnejad,Brandon Ginley,Pinaki Sarder,Avi Titievsky,Vadim V. Sharov,B. Ostretsov,Jeffrey B. Kopp,Avi Z. Rosenberg,Frank J. Gonzalez,Udayan Guha,Leonid Brodsky,Thomas P. Burris,Moshe Levi +24 more
TL;DR: Remarkably, only a 4-week treatment of 21-month-old mice with the pan ERR agonist reversed the age-related mitochondrial dysfunction, the cellular senescence marker p21, and inflammatory cytokines, including the STAT3 and STING signaling pathways.