Synthesis and structure–Activity relationship of 2-(aminoalkyl)-2,3,3a,8-tetrahydrodibenzo[c,f]isoxazolo[2,3-a]azepine derivatives: a novel series of 5-HT2A/2C receptor antagonists. Part 2

5.16 – Azepines

Tetracyclic heterocycles as CNS agents

Publisher Summary This chapter covers the eight-membered rings with two nitrogen atoms in a 1,5-position to each other and their fused-ring analogues The nomenclature of 1,5-diazocines is similar to that for azocines and 1 ,4 diazocines, especially the latter The completely conjugated compound is called 1,5-diazocine The partially saturated derivatives are prefixed dihydro, tetrahydro, etc The totally saturated compound is called perhydro-l,5-diazocine or 1,5- diazacyclooctane This chapter highlights the preparative methods, theoretical and structural studies, and various other reactions involving diazocines Lastly, the chapter also lists out the various applications of diazocines and its analogues

1,5-Diazocinesface

Morphanthridines I. 11-aminoalkylidene-and ll-(4-Piperidylene)-5,6-dihydromorphanthridines

Neurotrope und psychotrope substanzen II. Morphanthridin und derivate. Neue synthese des propazepins

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Neurotrope und psychotrope substanzen II. Morphanthridin und derivate. Neue synthese des propazepins