B. Gomes
University Health Network
8 Papers
9 Citations
B. Gomes is an academic researcher from University Health Network. The author has contributed to research in topics: Lung & Medicine. The author has an hindex of 2, co-authored 6 publications.
Chat about Author
Papers
Static lung storage at 10°C maintains mitochondrial health and preserves donor organ function.
Aadil Ali,Aizhou Wang,R. Ribeiro,Erika L. Beroncal,Cristina Baciu,M. Galasso,B. Gomes,A. Mariscal,Olivia Hough,Edson Brambate,Etienne Abdelnour-Berchtold,V. Michaelsen,Yu Zhang,A. Gazzalle,Eddy Fan,Laurent Brochard,Laurent Brochard,Jonathan C. Yeung,Thomas K. Waddell,Mingyao Liu,Ana Cristina Andreazza,Shaf Keshavjee,Marcelo Cypel +22 more
TL;DR: In this article, cold static preservation on ice (~4°C) remains the clinical standard of donor organ preservation, however, mitochondrial injury develops during prolonged storage, which limits the extent of time th...
67
Normothermic Regional Perfusion (NRP) during Heart DCD Recovery: Is Lung Quality Impacted? A Pre-Clinical Study
B. Gomes,R. Ribeiro,J. Alvarez,A.R. Honjeu,A. Gazzalle,Ved Bissoondath,F. Yu,Mitchell B. Adamson,Massimiliano Meineri,Vivek Rao,Mitesh V. Badiwala,Shaf Keshavjee,Marcelo Cypel +12 more
TL;DR: During NRP for heart procurement gas exchange function is preserved before and after NRP and no statistical differences in pulmonary compliance is seen and further studies transplanting lungs subjected to NRP should be performed before safe translation to clinical practice.
7
Addition of Dialysis to Ex-Vivo Lung Perfusion Maintains Homeostasis and Stability of Donor Lungs: A Pilot Study
Olivia Hough,X. Gao,Chengliang Yang,M. Takahashi,A. Mariscal,A.I. Nykanen,B. Gomes,Aadil Ali,Marcelo Cypel,Charles K. Chan,Shaf Keshavjee,Mingyao Liu +11 more
TL;DR: Dialysis may preserve lung function and length of EVLP by maintaining homeostasis of the lung and prolong EVLP duration in this encouraging pilot study.
3
Targeting Latent Human Cytomegalovirus (CMV) with a Novel Fusion Toxin Protein during Ex Vivo Lung Perfusion
R. Vp Ribeiro,Terrance Ku,Victor H Ferreira,M. Galasso,S. Moshkelgosha,V. Michaelsen,Aizhou Wang,Aadil Ali,Khaled Ramadan,B. Gomes,Layla Pires,H. Gokhale,A. Gazzalle,John Sinclair,Thomas N Kledal,Mingyao Liu,Shaf Keshavjee,Atul Humar,Marcelo Cypel +18 more
TL;DR: It is demonstrated that ex vivo F49A-FTP treatment of human lungs on EVLP markedly attenuates CMV reactivation, and ongoing ex vivo and in vivo reactivation experiments will confirm these findings.
3
Assessment of cerebral perfusion and activity during normothermic regional perfusion in a porcine model of donation after circulatory death
R. Ribeiro,B. Gomes,Arnaud Romeo Mbadjeu Hondjeu,F. Yu,Mitchell B. Adamson,J. Alvarez,Ved Bissoondath,Massimiliano Meineri,Vivek Rao,Marcelo Cypel,Mitesh V. Badiwala +10 more
1