B. Espina
10 Papers
B. Espina is an academic researcher. The author has contributed to research in topics: Medicine & Adipose tissue. The author has an hindex of 1, co-authored 1 publications.
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Papers
Long-term results of a prospective randomized trial of midline laparotomy closure with onlay mesh
TL;DR: The protective effect of the use of an onlay mesh in abdominal wall closure is significantly maintained in the long-term, up to 5 years after surgery.
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The Gut Microbiota Metabolite Succinate Promotes Adipose Tissue Browning in Crohn’s Disease
Diandra Monfort-Ferré,Aleidis Caro,M. Menacho,Marc Martí,B. Espina,A. Boronat-Toscano,Cati Nuñez-Roa,Jesús Seco,Michelle Bautista,Eloy Espin,Ana Megia,Joan Vendrell,Sonia Fernández-Veledo,Carolina Serena +13 more
TL;DR: In this paper , the authors evaluated the presence of beige AT depots in Crohn's disease and questioned whether succinate and/or bacterial translocation promoted white-to-beige transition in adipocytes.
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Anti-TNF Therapies Suppress Adipose Tissue Inflammation in Crohn’s Disease
A. Boronat-Toscano,Diandra Monfort-Ferré,M. Menacho,Aleidis Caro,Ramon Bosch,B. Espina,Francisco Algaba-Chueca,Alfonso Saera-Vila,Alicia Moliné,Marc Martí,Eloy Espin,Mónica Millán,Carolina Serena +12 more
TL;DR: Evidence is provided that anti-TNF medications influence immune cells and progenitor cells in the creeping of patients with Crohn’s disease, suppressing inflammation and it is proposed that perilesional VAT should be considered when administering anti- TNF therapy in patients with CD.
Genome-wide DNA methylome and transcriptome profiling reveals key genes involved in the dysregulation of adipose-stem cells in Crohn's disease.
Diandra Monfort-Ferré,A Boronat-Toscano,Jose Francisco Sánchez-Herrero,Aleidis Caro,M. Menacho,I. Vañó-Segarra,Marc Martí,B. Espina,Raquel Pluvinet,L. Cabrinety,C. Abadia,Miriam Ejarque,Cati Nuñez-Roa,Elsa Maymó-Masip,L. Sumoy,J. Vendrell,Sonia Fernández-Veledo,Carolina Serena +17 more
TL;DR: Genome-wide DNA methylome and transcriptome profiling identify novel genes involved in the dysregulation of adipose-stem cells in Crohn's disease.
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P083 An integrative analysis of DNA methylation and RNA-Seq data in human adipose-stem cells of Crohn’s Disease patients with different clinical activity
Cho Yin Ling Serena,D. Montfort-Ferré,Aleidis Caro,M. Menacho,B. Espina,A. Boronat-Toscano,Marc Martí,Eloy Espin,Mónica Millán,J A Vendrell,Sonia Fernández-Veledo +10 more
TL;DR: It is revealed that adipose-stem cells (hASCs) isolated from the creeping fat of CD subjects are dysfunctional (showing a high inflammatory profile, high invasive and phagocytic capacities, and worse immunosuppressive properties); and this dysfunction is maintained even in hASCs isolated from CD subjects in remission of the disease.