B. Chodkowski

TL;DR: A novel magnetization-transfer-weighted imaging approach was used to quantify damage to spinal white matter columns and tested its association with sensorimotor impairment and found that the dorsal column cerebrospinal-fluid-normalized magnetization -transfer signal specifically correlated with vibration sensation and the lateral column signal with strength.

TL;DR: MR imaging abnormalities specific to the motor tract are associated with clinical dysfunction related to that tract, and the relevant abnormalities are found in the brain stem, distant from the periventricular inflammatory lesions that are common in MS.

TL;DR: It is demonstrated that DTI of the cervical spinal cord can reliably discriminate sensory (dorsal) and motor (lateral) columns and column‐specific MR measurements are expected to enhance understanding of the intimate structure‐function relationship in the cervical spine and may be useful for the assessment of disease progression.

TL;DR: P pulsed ASL has the potential to be used for CBF comparison in longitudinal studies and a moderate level of reliability was obtained over a 1-year period, which was attributed to variance in slice positioning and coregistration.