B. Bravi
22 Papers
5 Citations
B. Bravi is an academic researcher. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 2, co-authored 10 publications.
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Papers
Cognitive remediation therapy for post-acute persistent cognitive deficits in COVID-19 survivors: A proof-of-concept study.
M. Palladini,B. Bravi,Federica Colombo,E. Caselani,Camilla di Pasquasio,G. D'Orsi,Patrizia Rovere-Querini,Sara Poletti,Francesco Benedetti,Mario Gennaro Mazza +9 more
TL;DR: In this paper , a case-control study investigated the efficacy of a CRT program administered to COVID-19 survivors in the post-acute phase of the illness, and found a significant effect over time of the CRT programme on global cognitive functioning.
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The role of opportunistic quantitative computed tomography in the evaluation of bone disease and risk of fracture in thalassemia major
Aldo Carnevale,Fabio Pellegrino,B. Bravi,Maria Rita Gamberini,Irene Gagliardi,Roberto Reverberi,Maria Chiara Zatelli,C. Giganti,Maria Rosaria Ambrosio +8 more
TL;DR: In this article , the correlation between quantitative CT (QCT) and dual energy X-ray absorptiometry (DXA) derived parameters was investigated for predicting the risk of fracture.
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Predicting Suicide Attempts among Major Depressive Disorder Patients with Structural Neuroimaging: A Machine Learning Approach
L. Fortaner-Uyà,C Monopoli,Federico Calesella,Francesca Colombo,B. Bravi,Emanuela Maggioni,E. Tassi,Sara Poletti,Irene Bollettini,F. Benedetti,Benedetta Vai +10 more
TL;DR: Overall, although overcoming the random classification accuracy (i.e., 50%), performances of all models classifying SA and nSA MDD patients were moderate, possibly due to the imbalanced numerosity of classes, with SVM on FA reaching the highest accuracy.
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Different effect of adverse childhood experiences on white matter microstructure in major depression and bipolar disorder: moderating role of genetic liability.
Marco Paolini,L. Raffaelli,V. Bettonagli,Cristina Lorenzi,Sara Spadini,B. Bravi,L. Fortaner-Uyà,Giulia Gulino,C. Fabbri,A. Serretti,Raffaella Zanardi,C. Colombo,Francesco Benedetti,Sara Poletti +13 more
Abstract: Adverse childhood experiences (ACEs) are risk factors for both major depressive (MDD) and bipolar disorder. ACEs have been associated with white matter (WM) alterations, but whether they have different effects in MDD and BD remains unclear. Polygenic risk scores (PRS) allow for an individual estimation of genetic liabilities for most psychiatric conditions. The aim of the present study was to characterize the effect of ACEs on WM microstructure in MDD and BD, testing a possible differential effect between the two diagnoses and investigating whether genetic liabilities might modulate this relation. 260 depressed inpatients (140 MDD and 120 BD, mean age 49.29 ± 10.60, F = 161) underwent 3T MRI scan and ACEs evaluation. MDD and BD PRS were calculated in a subset of patients. Significant ACEs x diagnosis interactions were found for several DTI metrics. Single group analyses showed widespread detrimental effects of ACEs on WM integrity in BD, and less pronounced effects in MDD. Significant moderating effect of BD PRS in the whole sample and in MDD specifically were found for the relation between ACEs, fractional anisotropy and radial diffusivity, with bipolar-like relations for higher values of BD PRS. The differential effect of ACEs on WM microstructure in the two diagnostic groups points towards putative differential pathophysiological routes through which childhood maltreatment affects the two conditions, while the identification of a BD PRS moderation on the whole sample and in MDD specifically sheds light on the causal relation between ACEs, diagnostic phenotype and DTI metrics, and provides a possible tool to disentangle MDD heterogeneity.