B Barthel
Free University of Berlin
10 Papers
194 Citations
B Barthel is an academic researcher from Free University of Berlin. The author has contributed to research in topics: Apoptosis & Cell cycle checkpoint. The author has an hindex of 8, co-authored 8 publications.
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Papers
Extracellular nucleotides inhibit growth of human oesophageal cancer cells via P2Y(2)-receptors.
Kerstin Maaser,Michael Höpfner,H Kap,A P Sutter,B Barthel,B von Lampe,Martin Zeitz,Hans Scherübl +7 more
TL;DR: The pharmacological features strongly suggest the functional expression of G-protein coupled P2Y2-receptors are promising target proteins for innovative approaches in oesophageal cancer therapy.
Growth inhibition and apoptosis induced by P2Y2 receptors in human colorectal carcinoma cells: involvement of intracellular calcium and cyclic adenosine monophosphate.
Michael Höpfner,Kerstin Maaser,B Barthel,B von Lampe,Christoph Hanski,Ernst-Otto Riecken,Martin Zeitz,Hans Scherübl +7 more
TL;DR: The results demonstrate the growth inhibitory potency of P2Y2 receptors in colorectal carcinoma cells and appears to play a major role in the observed antiproliferative and apoptosis-inducing effects.
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Specific ligands of the peripheral benzodiazepine receptor induce apoptosis and cell cycle arrest in human esophageal cancer cells
A P Sutter,Kerstin Maaser,Michael Höpfner,B Barthel,Patricia Grabowski,S. Faiss,Pierre Carayon,Martin Zeitz,Hans Scherübl +8 more
TL;DR: PBR‐specific ligands are qualified as innovative proapoptotic and antiproliferative substances that might prove suitable for the treatment of esophageal cancer.
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Ligands of the peripheral benzodiazepine receptor induce apoptosis and cell cycle arrest in oesophageal cancer cells: involvement of the p38MAPK signalling pathway
TL;DR: Data indicate that PBR-specific ligands cause apoptosis and cell cycle arrest by activation of the p38MAPK pathway and induction of gadd45 and gadd153, in response to PBR ligands.
Oesophageal squamous cell neoplasia in head and neck cancer patients: upregulation of COX-2 during carcinogenesis
Kerstin Maaser,P Däubler,B Barthel,Bernhard Heine,B von Lampe,Harald Stein,Bodo Hoffmeister,H. Scherer,Hans Scherübl +8 more
TL;DR: It is suggested that COX-2 upregulation contributes to oesophageal squamous carcinogenesis in HNC patients and future studies are needed to evaluate the chemopreventive potential of COx-2 inhibitors in this high-risk group.