Aya Shimada
Children's Medical Center of Dallas
7 Papers
21 Citations
Aya Shimada is an academic researcher from Children's Medical Center of Dallas. The author has contributed to research in topics: Hydrocortisone & Adrenal crisis. The author has an hindex of 2, co-authored 6 publications.
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Papers
A Novel Mutation in OTX2 Causes Combined Pituitary Hormone Deficiency, Bilateral Microphthalmia, and Agenesis of the Left Internal Carotid Artery
TL;DR: This study reports a novel missense OTX2 (R89P) mutation in a CPHD patient with severe hypoglycemia in the neonatal period due to ACTH deficiency, bilateral microphthalmia, and agenesis of the left internal carotid artery (ICA).
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Intracrine activity involving NAD-dependent circadian steroidogenic activity governs age-associated meibomian gland dysfunction
Lena Sasaki,Yuki Hamada,Daisuke Yarimizu,Tomo Suzuki,Hiroki Nakamura,Aya Shimada,Khanh Tien Nguyen Pham,Xinyan Shao,Koki Yamamura,Tsutomu Inatomi,Hironobu Morinaga,Emi K. Nishimura,Fujimi Kudo,Ichiro Manabe,Shogo Haraguchi,Yuki Sugiura,Makoto Suematsu,Shigeru Kinoshita,Mamiko Machida,Takeshi Nakajima,Hiroshi Kiyonari,Hitoshi Okamura,Yoshiaki Yamaguchi,Takahito Miyake,Masao Doi +24 more
TL;DR: In this article , the authors demonstrate that reactivation of local intracrine activity through nicotinamide adenine dinucleotide (NAD + )-dependent circadian 3β-hydroxyl-steroid dehydrogenase (3β-HSD) activity ameliorates age-associated meibomian gland dysfunction and accompanying evaporative dry eye disease.
ESPE Position Statement for Paediatric Endocrinology Subspecialty
Ahmad R. Ramadan,Said M. Shawar,Manal A. Alghamdi,William Drake,Ashley B. Grossman,Martin O. Savage,Helen L Storr,Lucy Shapiro,Shezan Elahi,Fiona Riddoch,Leslie A. Perry,Lee Martin,Scott Akker,John P. Monson,Rasha T. Hamza,Amel A. Elfaramawy,Nermine H. Mahmoud,Pamela Fischer-Posovszky,Primoz Kotnik,Tadej Battelino,Valerio Nobili,Stefano Cianfarani,Martin Wabitsch,Julian Roos,Elena Inzaghi,Francesco Massart,Mario Miccoli,Silvano Bertelloni,Hanna Borysewicz-Sańczyk,Janusz Dzięcioł,Beata Sawicka,Artur Bossowski,Jami L. Josefson,Robert Listernick,Joel Charrow,Reema L. Habiby,Sandro Loche,Marco Cappa,Ottavia Porzio,Arianna Massimi,Luca Federici,Antonio Cualbu,Lorenza Bellincampi,Sergio Bernardini,Carla Bizzarri,Yukihiro Hasegawa,Masaki Takagi,Aya Shimada,Kentaro Miyai,Yuka Nagashima,Satz Mengensatzproduktion,Werner Druck Medien Ag +51 more
TL;DR: Paediatric Endocrinology, under the leaderships of Lawson Wilkins in the US and of Andrea Prader in Europe, started to take shape as a subspecialty in the 1960s and has developed at a tremendous speed, especially during the last 30 years, in line with increasing knowledge in the field of genetics and other basic sciences.
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A case of spondyloepiphyseal dysplasia tarda caused by a novel intragenic deletion of TRAPPC2
Masaki Takagi,Hiroko Yagi,Yoshie Nakamura,Hiroyuki Shinohara,Ryojun Takeda,Aya Shimada,Gen Nishimura,Yukihiro Hasegawa +7 more
TL;DR: A Japanese SEDT patient is reported with a novel intragenic deletion mutation in TRAPPC2, which encodes trafficking protein particle complex subunit 2, a 140 amino acid protein, also known as Sedlin.
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Five cases of childhood-onset Graves' disease treated with either surgery or radio-iodine therapy.
TL;DR: Surgery and RAI therapy could be good alternative treatment options for children with Graves’ disease following an unfavorable outcome of initial ATD treatment.
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