Aurea Lima
University of Porto
24 Papers
39 Citations
Aurea Lima is an academic researcher from University of Porto. The author has contributed to research in topics: Rheumatoid arthritis & Medicine. The author has an hindex of 12, co-authored 23 publications. Previous affiliations of Aurea Lima include Instituto Português de Oncologia Francisco Gentil & Instituto Politécnico Nacional.
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Papers
Current approaches for TYMS polymorphisms and their importance in molecular epidemiology and pharmacogenetics.
TL;DR: Early identification of individuals at risk of disease along with improvement in the prediction of patients' outcome will offer a powerful tool for the translation of TYMS polymorphisms into clinical practice and individualization of treatments.
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Prediction of Methotrexate Clinical Response in Portuguese Rheumatoid Arthritis Patients: Implication of MTHFR rs1801133 and ATIC rs4673993 Polymorphisms
Aurea Lima,Joaquim Monteiro,Miguel Bernardes,Hugo Sousa,Rita Azevedo,Vítor Seabra,Rui Medeiros +6 more
TL;DR: It is suggested that MTHFR C677T and ATIC T675C genotyping combined with clinicopathological data may help to identify patients whom will not benefit from MTX treatment and, therefore, assist clinicians in personalizing RA treatment.
Role of Key TYMS Polymorphisms on Methotrexate Therapeutic Outcome in Portuguese Rheumatoid Arthritis Patients
TL;DR: It is revealed that TYMS polymorphisms could be important to help predicting clinical response to MTX in RA patients, and translation into clinical practice needs larger studies to confirm these evidences.
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Smartphone application for rheumatoid arthritis self-management: cross-sectional study revealed the usefulness, willingness to use and patients’ needs
TL;DR: The usefulness of a smartphone application to support rheumatoid arthritis self-management, the willingness of RA patients to use and pay for it and the features the application should have are evaluated.
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Liquid chromatographic methods for the therapeutic drug monitoring of methotrexate as clinical decision support for personalized medicine: A brief review.
Mónica Francisco Silva,Cláudia Ribeiro,Virgínia M.F. Gonçalves,Maria Elizabeth Tiritan,Aurea Lima +4 more
TL;DR: The most commonly used techniques for sample preparation are reviewed and the current LC methods applied for the TDM of MTX in biological samples, at LDMTX and HDMTX are critically discussed.
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