Atsushi Miyajima
University of Tokyo
370 Papers
6.3K Citations
Atsushi Miyajima is an academic researcher from University of Tokyo. The author has contributed to research in topics: Signal transduction & Biology. The author has an hindex of 89, co-authored 360 publications. Previous affiliations of Atsushi Miyajima include St. Jude Children's Research Hospital & Institute of Medical Science.
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Papers
Lack of Oncostatin M Receptor β Leads to Adipose Tissue Inflammation and Insulin Resistance by Switching Macrophage Phenotype
TL;DR: OSM suppresses the development of insulin resistance at least in part through the polarization of the macrophage phenotypes to M2, and OSMRβ−/− mice provide a unique mouse model of metabolic diseases.
Identification and isolation of adult liver stem/progenitor cells.
Minoru Tanaka,Atsushi Miyajima +1 more
TL;DR: Here, the identification and isolation of mouse liver stem/progenitor cells is described by utilizing antibodies against specific cell surface marker molecules.
Characterization of cell phenotype by a novel cDNA library subtraction system: expression of CD8 alpha in a mast cell-derived interleukin-4-dependent cell line.
TL;DR: This study demonstrates the effective use of the cDNA library subtraction strategy to characterize unknown types of hematopoietic cells at the molecular level.
Mitochondria and apicoplast of Plasmodium falciparum: behaviour on subcellular fractionation and the implication.
Tamaki Kobayashi,Shigeharu Sato,Shinzaburo Takamiya,Kanako Komaki-Yasuda,Kazuhiko Yano,Ayami Hirata,Izumi Onitsuka,Masayuki Hata,Fumika Mi-ichi,Takeshi Tanaka,Toshiharu Hase,Atsushi Miyajima,Shin-ichiro Kawazu,Yoh-ichi Watanabe,Kiyoshi Kita +14 more
TL;DR: To the surprise, the apicoplast was inseparable from the plasmodial mitochondrion by each method, which implies these two plas modial organelles are bound each other, the first experimental evidence of a physical binding between the two organelle in Plasmodium.
miR-148a plays a pivotal role in the liver by promoting the hepatospecific phenotype and suppressing the invasiveness of transformed cells.
Luc Gailhouste,Laura Gomez-Santos,Keitaro Hagiwara,Izuho Hatada,Noriyuki Kitagawa,Kazushi Kawaharada,Muriel Thirion,Nobuyoshi Kosaka,Ryou U. Takahashi,Tatsuhiro Shibata,Atsushi Miyajima,Takahiro Ochiya +11 more
TL;DR: This report is the first to demonstrate a functional role for a specific miRNA in liver development through regulation of the DNMT1 enzyme and shows that miR‐148a is essential for the physiology of the liver because it promotes the hepatospecific phenotype and acts as a tumor suppressor.