Atsunori Kashiwagi
Shiga University of Medical Science
429 Papers
5.1K Citations
Atsunori Kashiwagi is an academic researcher from Shiga University of Medical Science. The author has contributed to research in topics: Diabetes mellitus & Type 2 diabetes. The author has an hindex of 72, co-authored 423 publications. Previous affiliations of Atsunori Kashiwagi include Shiga University & University of California, Los Angeles.
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Papers
Increased intestinal glucose absorption and postprandial hyperglycaemia at the early step of glucose intolerance in Otsuka Long-Evans Tokushima Fatty rats.
Yukihiro Fujita,Hideto Kojima,Hideki Hidaka,Mineko Fujimiya,Atsunori Kashiwagi,Ryuichi Kikkawa +5 more
TL;DR: Results suggest that an increased SGLT1 expression concomitant with intestinal hypertrophy in OLETF rats is partly associated with postprandial hyperglycaemia before the onset of insulin resistance and hyperinsulinaemia.
Omega-3 polyunsaturated fatty acid has an anti-oxidant effect via the Nrf-2/HO-1 pathway in 3T3-L1 adipocytes
Chisato Kusunoki,Liu Yang,Takeshi Yoshizaki,Fumiyuki Nakagawa,Atsushi Ishikado,Motoyuki Kondo,Katsutaro Morino,Osamu Sekine,Satoshi Ugi,Yoshihiko Nishio,Atsunori Kashiwagi,Hiroshi Maegawa +11 more
TL;DR: Treatment with EPA and DHA induced HO-1 through the activation of Nrf-2 and prevented oxidative stress in 3T3-L1 adipocytes, suggesting this anti-oxidant defense may be of high therapeutic value for clinical conditions associated with systemic oxidative stress.
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Altered activities of transcription factors and their related gene expression in cardiac tissues of diabetic rats.
Yoshihiko Nishio,Atsunori Kashiwagi,Hideki Taki,Kazuya Shinozaki,Yasuhiro Maeno,Hideto Kojima,Hiroshi Maegawa,Masakazu Haneda,Hideki Hidaka,Hitoshi Yasuda,Kihachiro Horiike,Ryuichi Kikkawa +11 more
TL;DR: Elevated oxidative stress is involved in the activation of the transcription factors NF-KB and AP-1 in the cardiac tissues of diabetic rats, and that these abnormal activities of transcription factors could be associated with the altered gene regulation observed in the cardiovascular tissues of diabetes rats.
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Ipragliflozin improves glycemic control in Japanese patients with type 2 diabetes mellitus: the BRIGHTEN study
Atsunori Kashiwagi,Kenichi Kazuta,Yuusuke Takinami,Satoshi Yoshida,Atsushi Utsuno,Itsuro Nagase +5 more
TL;DR: Treatment with 50 mg ipragliflozin once daily for 16 weeks achieved significant improvements in HbA1c, FPG, body weight, and waist circumference compared with placebo in Japanese patients with T2DM.
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