Atsuhiro Kanayama
University of Tokyo
14 Papers
254 Citations
Atsuhiro Kanayama is an academic researcher from University of Tokyo. The author has contributed to research in topics: Taurine & Platinum nanoparticles. The author has an hindex of 10, co-authored 14 publications. Previous affiliations of Atsuhiro Kanayama include National Defense Medical College.
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Papers
Platinum nanoparticle is a useful scavenger of superoxide anion and hydrogen peroxide
Masashi Kajita,Keisuke Hikosaka,Mayumi Iitsuka,Atsuhiro Kanayama,Naoki Toshima,Yusei Miyamoto +5 more
TL;DR: CP-Pt may be a SOD/catalase mimetic which is useful for medical treatment of oxidative stress diseases and quenched hydrogen peroxide and superoxide anion radical in dose-dependent manners.
295
In vitro free radical scavenging activity of platinum nanoparticles.
Aki Watanabe,Masashi Kajita,Juewon Kim,Atsuhiro Kanayama,Atsuhiro Kanayama,Kyoko Takahashi,Tadahiko Mashino,Yusei Miyamoto +7 more
TL;DR: Observations suggest that PAA-Pt is an efficient scavenger of free radicals and is durable, and reduces the rate of oxygen consumption required for linoleic acid peroxidation initiated by AAPH.
193
Oxidation of IκBα at Methionine 45 Is One Cause of Taurine Chloramine-induced Inhibition of NF-κB Activation
TL;DR: Results indicate that Met45 oxidation of IκBα is a molecular mechanism underlying the TauCl-induced inhibition of NF-κB activation and may help suppress excessive inflammatory reaction in neutrophils.
142
Two Mechanistically and Temporally Distinct NF-κB Activation Pathways in IL-1 Signaling
Kohsuke Yamazaki,Jin Gohda,Atsuhiro Kanayama,Yusei Miyamoto,Hiroaki Sakurai,Masahiro Yamamoto,Shizuo Akira,Hidetoshi Hayashi,Bing Su,Jun-ichiro Inoue +9 more
TL;DR: TAK1-mediated activation of NF-κB required the transient formation of a signaling complex that included tumor necrosis factor receptor–associated factor 6 (TRAF6), MEKK3, and TAK1, which was required for the production of sufficient cytokines.
129
Apoptosis triggered by phagocytosis-related oxidative stress through FLIPS down-regulation and JNK activation.
Atsuhiro Kanayama,Yusei Miyamoto +1 more
TL;DR: Results indicate that the antiapoptotic signaling induced by TNF‐α via NF‐κB activation can be altered to promote apoptosis via H2O2‐MPO‐mediated FLIPS down‐regulation and JNK activation.
46