Assia Chaibi
Argonne National Laboratory
9 Papers
2 Citations
Assia Chaibi is an academic researcher from Argonne National Laboratory. The author has contributed to research in topics: Immune system & Cancer. The author has an hindex of 2, co-authored 3 publications.
Chat about Author
Papers
CD95/Fas protects triple negative breast cancer from anti-tumor activity of NK cells.
Abdul S. Qadir,Jean Philippe Guégan,Christophe Ginestier,Assia Chaibi,Alban Bessede,Emmanuelle Charafe-Jauffret,Manon Macario,Vincent Lavoué,Thibault De La Motte Rouge,Calvin Law,Jacob Vilker,Hongbin Wang,Emily Kunce Stroup,Matthew J. Schipma,Bryan B. Bridgeman,Andrea E. Murmann,Zhe Ji,Patrick Legembre,Marcus E. Peter +18 more
TL;DR: In this article, the authors used a combination of immune-deficient and immune-competent mouse models to establish that loss of CD95 in metastatic triple negative breast cancer (TNBC) cells prevents tumor growth by modulating the immune landscape.
14
Tumor expressed CD95 causes suppression of anti-tumor activity of NK cells in a model of triple negative breast cancer
A. S. Qadir,Jean Philippe Guégan,Christophe Ginestier,Assia Chaibi,A. Bessede,Emmanuelle Charafe-Jauffret,Manon Macario,Vincent Lavoué,T. de la Motte Rouge,Calvin Law,Jacob Vilker,Haiyan Wang,Emily Kunce Stroup,Matthew J. Schipma,Bryan B. Bridgeman,Andrea E. Murmann,Zhe Ji,Patrick Legembre,Marcus E. Peter +18 more
TL;DR: In this paper, a combination of immune-deficient and immune-competent mouse models was used to demonstrate that loss of CD95 in metastatic triple negative breast cancer cells prevents tumor growth by modulating the immune landscape.
Abstract 4705: Profiling of immune cell components and soluble factors in ovarian cancer ascites highlights impaired immune environment
Assia Chaibi,Coriolan Lebreton,D. Bodet,Jean-Philippe Guégan,Guillaume Babin,Antoine Italiano,Alban Bessede,Imane Nafia +7 more
TL;DR: Chaibi et al. as mentioned in this paper showed that ascites fluids most favorable to the M2 phenotype were associated with high LIF, VEGF, IL6, CCL2, and CCL18 levels, and with elevated Kyn to Trp ratios.
1426 Comprehensive analysis of a novel anti-PDL1 resistant sarcoma mouse model
Alban Bessede,Jean-Philippe Guégan,Imane Nafia,Assia Chaibi,Christophe Rey,Oren Ngouala,Florent Peyraud,Antoine Italiano +7 more
- 01 Nov 2022
TL;DR: In this paper , the authors developed and validated a novel preclinical mouse model of sarcoma (MCA205-R) characterized by its resistance to anti-PD1 and a high tumor infiltration by macro-phages.
Abstract 2527: Ovarian cancer ascites display altered immune environment featured by enhanced soluble factors and suppressive cellular context
Imane Nafia,Assia Chaibi,Christophe Rey,Jean-Philippe Guégan,Alban Bessede,Coriolan Lebreton,Antoine Italiano +6 more
TL;DR: Translational findings highlight ovarian patient-derived ascites as a valuable tool to understand the mechanisms of suppression and to allow for the identification of novel markers to develop innovative targeted therapies.