Ashutosh Sharma
University of Illinois at Chicago
24 Papers
61 Citations
Ashutosh Sharma is an academic researcher from University of Illinois at Chicago. The author has contributed to research in topics: Chemistry & Lipid droplet. The author has an hindex of 9, co-authored 16 publications. Previous affiliations of Ashutosh Sharma include Central Drug Research Institute & Indian Institute of Technology Madras.
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Papers
Structural Basis for Cholesterol Transport-like Activity of the Hedgehog Receptor Patched.
Yunxiao Zhang,David Bulkley,Yao Xin,Kelsey J. Roberts,Daniel Asarnow,Ashutosh Sharma,Benjamin R. Myers,Wonhwa Cho,Yifan Cheng,Philip A. Beachy +9 more
TL;DR: Cholesterol activity in the inner leaflet of the plasma membrane is reduced by PTCH1 expression but rapidly restored by Hedgehog stimulation, suggesting thatPTCH1 regulates Smoothened by controlling cholesterol availability.
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New fluoranthene FLUN-550 as a fluorescent probe for selective staining and quantification of intracellular lipid droplets.
Atul Goel,Ashutosh Sharma,Manoj Kathuria,Arindam Bhattacharjee,Ashwni Verma,Prabhat Ranjan Mishra,Aamir Nazir,Kalyan Mitra +7 more
TL;DR: A new class of live cell permeant, nontoxic fluoranthene-based fluorescent probe (FLUN-550) having a high Stokes shift in aqueous medium has been discovered and showed selective staining of lipid droplets at a low concentration without background noise in in vitro live cell imaging.
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A dual colorimetric-ratiometric fluorescent probe NAP-3 for selective detection and imaging of endogenous labile iron(III) pools in C. elegans.
Atul Goel,Shahida Umar,Pankaj Nag,Ashutosh Sharma,Lalit Kumar,Shamsuzzama,Zakir Hossain,Jiaur R. Gayen,Aamir Nazir +8 more
TL;DR: The first dual colorimetric and ratiometric fluorescent probe naphtho[2,1-b][1,10]phenanthroline for selective and 'direct' visualization of labile iron(III) pools in a multicellular organism, Caenorhabditis elegans is reported.
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A new type of biocompatible fluorescent probe AFN for fixed and live cell imaging of intracellular lipid droplets
TL;DR: A new class of nontoxic, highly fluorogenic and biocompatible probe AFN for selective staining of intracellular Lipid Droplets in both fixed and live human cervical cancer cells and 3T3-L1 pre-adipocytes is discovered.
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A Nonarchetypal 5,6‐Dihydro‐2H‐pyrano[3,2‐g]indolizine‐Based Solution‐Solid Dual Emissive AIEgen with Multicolor Tunability
Ashutosh Raghuvanshi,Ajay Kumar Jha,Ashutosh Sharma,Shahida Umar,Shachi Mishra,Ruchir Kant,Atul Goel,Atul Goel +7 more
TL;DR: DPI-7 is the first example of solution-solid dual emissive RIV-based AIEgen, which has great potential both in biomedical imaging and optoelectronic fields.
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