Ashutosh Mishra
Indian Institute of Science
3 Papers
Ashutosh Mishra is an academic researcher from Indian Institute of Science. The author has contributed to research in topics: Population & Signal processing. The author has an hindex of 2, co-authored 3 publications.
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Papers
A mechanistic model captures the emergence and implications of non-genetic heterogeneity and reversible drug resistance in ER+ breast cancer cells.
Sarthak Sahoo,Ashutosh Mishra,Harsimran Kaur,Kishore Hari,Srinath Muralidharan,Susmita Mandal,Mohit Kumar Jolly +6 more
- 02 Jul 2021
TL;DR: In this article, the authors investigated coupled dynamics of epithelial-mesenchymal transition (EMT) in breast cancer cells and emergence of reversible drug resistance and proposed the potential therapeutic use of mesenchym-epithelial transition inducers besides canonical anti-estrogen therapy to limit the emergence of drug resistance.
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Comparison of Matching Pursuit Algorithm with Other Signal Processing Techniques for Computation of the Time-Frequency Power Spectrum of Brain Signals
TL;DR: A multiscale decomposition technique based on an over-complete dictionary called matching pursuit (MP) is described, and it is shown that it is able to capture both a sharp stimulus-onset transient and a sustained gamma rhythm in local field potential recorded from the primary visual cortex.
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A mechanistic model captures the emergence and implications of non-genetic heterogeneity and reversible drug resistance in ER+ breast cancer cells
Sarthak Sahoo,Ashutosh Mishra,Harsimran Kaur,Kishore Hari,Srinath Muralidharan,Susmita Mandal,Mohit Kumar Jolly +6 more
TL;DR: In this paper, the authors investigate coupled dynamics of epithelial-mesenchymal transition (EMT) in breast cancer cells and emergence of reversible drug resistance, and exemplify the implications of phenotypic plasticity and/or non-genetic heterogeneity in promoting population survival in a mixture of sensitive and resistant cells, even in the absence of any cell-cell cooperation.