Ashley M. Stokes
Barrow Neurological Institute
49 Papers
79 Citations
Ashley M. Stokes is an academic researcher from Barrow Neurological Institute. The author has contributed to research in topics: Medicine & Diffusion MRI. The author has an hindex of 13, co-authored 42 publications. Previous affiliations of Ashley M. Stokes include St. Joseph's Hospital and Medical Center & Western Illinois University.
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Papers
Hypoxia Imaging With PET Correlates With Antitumor Activity of the Hypoxia-Activated Prodrug Evofosfamide (TH-302) in Rodent Glioma Models.
Ashley M. Stokes,Charles P. Hart,C. Chad Quarles +2 more
- 01 Sep 2016
TL;DR: This work shows that imaging methods sensitive to tumor hypoxia and perfusion are able to predict response toHypoxia-targeted agents, which has implications for improved patient selection, particularly in clinical trials, for treatment with hypoxIA-activated cytotoxic prodrugs, such as evofosfamide.
Systematic assessment of multi-echo dynamic susceptibility contrast MRI using a digital reference object.
TL;DR: Using a computational approach, a wide range of acquisition strategies are evaluated to determine the optimal multi‐echo DSC‐MRI perfusion protocol.
Characterizing the Influence of Preload Dosing on Percent Signal Recovery (PSR) and Cerebral Blood Volume (CBV) Measurements in a Patient Population With High-Grade Glioma Using Dynamic Susceptibility Contrast MRI.
Laura C. Bell,Leland S. Hu,Ashley M. Stokes,Samuel McGee,Leslie C. Baxter,C. Chad Quarles +5 more
- 01 Jun 2017
TL;DR: The finding that leakage-corrected rCBV values do not depend on the presence or dose of preload contradicts that of previous studies with dissimilar acquisition protocols, and suggests that studies using PSR as a biomarker should acquire DSC-MRI data without preload.
Characterization of restricted diffusion in uni- and multi-lamellar vesicles using short distance iMQCs.
TL;DR: A new MRI method based on intermolecular double quantum coherences (iDQCs), which can probe the restricted diffusion characteristics at well-defined and tunable microscopic distance scales is proposed, which provides a mechanism to directly image vesicle entrapment, transport, and release.
Preliminary Assessment of Intravoxel Incoherent Motion Diffusion‐Weighted MRI (IVIM‐DWI) Metrics in Alzheimer's Disease
Maurizio Bergamino,Ashley Nespodzany,Leslie C. Baxter,Leslie C. Baxter,Anna D. Burke,Richard J. Caselli,Marwan N. Sabbagh,Ryan R. Walsh,Ashley M. Stokes +8 more
TL;DR: In this article, the authors investigated the connection between cognitive assessments and neuroimaging metrics, including voxel-based morphometry (VBM), apparent diffusion coefficient (ADC), and intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI) metrics in aging populations.