Ashley I. Bush

TL;DR: An important role for neuronal GSH homeostasis in selective protection against Cu toxicity is demonstrated, a finding with widespread implications for neurodegenerative disorders.

TL;DR: The potential long-term implications of excessive iron intake in early life are discussed, the analysis of iron deposits in teeth as a method for retrospective determination of iron exposure during critical developmental windows are proposed, and evidence-based optimization of the chemical composition of infant dietary supplements is proposed.

TL;DR: NAC may have an impact on cognitive performance in psychosis, as a significant improvement in working memory was observed in the NAC-treated group compared with placebo; however, these preliminary data require replication.

TL;DR: The results suggest that histidine and tyrosine are most vulnerable to metal mediated oxidative attack, consistent with the earlier findings that Cu coordinated via histidine residues is redox competent.