Ash A. Alizadeh

TL;DR: Compared to non-hematologic malignancies, distance to treatment center likely does not adversely influence outcomes for patients with AML, and after accounting for confounding factors, DTC has no significant impact on the outcome of newly diagnosed AML patients receiving care at the authors' institution.

TL;DR: This study takes first steps toward a comprehensive non-invasive classification of novel DLBCL genetic subtypes using a limited gene panel and describes 2 new classifiers applicable to plasma genotyping that are largely complementary to COO subtypes, and describe overlapping genotypes.

TL;DR: The clinical scenarios and key technologies applicable for the molecular monitoring of lymphomas are reviewed, summarizing current evidence in the literature regarding molecular subtyping and classification, evaluation of treatment response, the surveillance of active cellular therapies, and emerging clinical trial strategies.

TL;DR: The combination of array CGH and expression analysis provides a more comprehensive picture of the transformation of FCL to DLBCL, which is associated with the acquisition of a variable spectrum of genomic imbalances affecting recurrent chromosomal areas that harbor overexpressed or underexpressed genes targeted upon transformation.