Arturo Cardounel
VCU Medical Center
10 Papers
151 Citations
Arturo Cardounel is an academic researcher from VCU Medical Center. The author has contributed to research in topics: Amyloid beta & Neurotoxicity. The author has an hindex of 8, co-authored 10 publications.
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Papers
Apigenin-induced-apoptosis is mediated by the activation of PKCδ and caspases in leukemia cells
Melissa A. Vargo,Oliver H. Voss,Frantisek Poustka,Arturo Cardounel,Erich Grotewold,Andrea I. Doseff +5 more
TL;DR: Results indicate that this flavonoid provides selective activity to promote caspase-dependent-apoptosis of leukemia cells and uncover an essential role of PKCdelta during the induction of apoptosis by apigenin.
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Pregnenolone protects mouse hippocampal (HT-22) cells against glutamate and amyloid beta protein toxicity
TL;DR: Results show that pregnenolone has neuroprotective effects against both glutamate and amyloid beta protein neuropathology and prevention of glucocorticoid receptor (GR) localization to the nucleus may be involved in the observed neuroProtective effects of pregnenolsone against glutamate neurotoxicity.
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Biological effects of long-term caloric restriction: adaptation with simultaneous administration of caloric stress plus repeated immobilization stress in rats.
TL;DR: Several stress-related responses such as inhibition of total body weight gain, increased adrenal weight, decreased thymus weight, increased plasma corticosterone, and lipid peroxidation levels in the liver and heart are associated with Cal, but no additional effects were observed on the parameters that were measured when two stress regimens were given simultaneously.
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Biological effects of single and repeated swimming stress in male rats: beneficial effects of glucocorticoids.
TL;DR: Elevated plasma corticosterone levels by downregulating GR during repeated swimming stress exerts beneficial effects in rats by retarding the total body weight gain and lowering plasma triglyceride levels without affecting free-radicals-induced oxidative stress.
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Repeated immobilization stress increases total cytosolic glucocorticoid receptor in rat liver.
TL;DR: Novel results suggest that repeated stress influences the hypothalamic-pituitary-adrenal axis in rats by elevating both the level of plasma corticosterone and total hepatic cytosolic GR.
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