Artur M. S. Silva
University of Aveiro
976 Papers
4.9K Citations
Artur M. S. Silva is an academic researcher from University of Aveiro. The author has contributed to research in topics: Chemistry & Catalysis. The author has an hindex of 54, co-authored 895 publications. Previous affiliations of Artur M. S. Silva include University of Porto & University of Santiago de Compostela.
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Papers
Syntheses of Novel (E)-N-Methyl-2-styryl-4-quinolones
Andreia Almeida,Vera L. M. Silva,Artur M. S. Silva,Diana C. G. A. Pinto,José A. S. Cavaleiro +4 more
TL;DR: In this article, two synthetic routes for (E)-N-methyl-2-styryl-4-quinolones have been established, both starting from ( E)-2′-cinnamoylaminoacetophenones.
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Synthesis and structural characterisation of ring B oxidised derivatives of dehydroabietic acid
Silvia M. C. S. Monteiro,Armando J. D. Silvestre,Artur M. S. Silva,José A. S. Cavaleiro,Vítor Félix,Michael G. B. Drew +5 more
TL;DR: In this article, the synthesis and structural characterisation of new derivatives of dehydroabietic acid, oxidised in the 6 and 7 positions of ring B, were described and exhaustively characterised for the first time.
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Molecular docking and dynamic studies of a potential therapeutic target inhibiting glyoxalase system: Metabolic action of the 3, 3 '- [3- (5-chloro-2-hydroxyphenyl) -3-oxopropane-1, 1-diyl] - Bis-4-hydroxycoumarin leads overexpression of the intracellular level of methylglyoxal and induction of a pro-apoptotic phenomenon in a hepatocellular carcinoma model
Nadia Taibi,Qosay Al-Balas,Nadjia Bekari,Oualid Talhi,Ghazi A. Al Jabal,Yasmine Benali,Rachid Ameraoui,Mohamed Hadjadj,Amina Taïbi,Zahra Mouna Boutaiba,Mohamed Abou-mustapha,Farida Khammar,Fayçal Dergal,Ridha Hassaine,Leila Boukenna,Khaldoun Bachari,Artur M. S. Silva +16 more
TL;DR: In this article, the authors demonstrate the inhibitory effect of 3, 3'-[3-(5-chloro-2-hydroxyphenyl)-3-oxopropane-1, 1-diyl] Bis (4-hydroxycoumarin) on the glyoxalase system, and indirectly its anticancer activity.
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Elucidating the role of aromatic interactions in rotational barriers involving aromatic systems.
Carlos F. R. A. C. Lima,Carlos F. R. A. C. Lima,Ligia R. Gomes,John N. Low,Artur M. S. Silva,Luís M. N. B. F. Santos +5 more
TL;DR: The measurement of aryl-naphthyl rotational barriers in various solvents for two substituted 1,8-diarylnaphthalenes by dynamic (1)H NMR showed that ΔG(‡) trends in aromatic systems can be fully rationalized only when considering the different types of aromatic interactions.
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