Arthur Taylor
University of Liverpool
46 Papers
202 Citations
Arthur Taylor is an academic researcher from University of Liverpool. The author has contributed to research in topics: Medicine & Mesenchymal stem cell. The author has an hindex of 22, co-authored 46 publications. Previous affiliations of Arthur Taylor include Universidade Federal de Santa Catarina & Leibniz Association.
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Papers
Long-term tracking of cells using inorganic nanoparticles as contrast agents: are we there yet?
TL;DR: What the current literature can teach us in respect to cell interactions with inorganic nanoparticles, with the perspective of using them as probes for cell labelling, is looked at.
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Single-wall carbon nanotubes based anticancer drug delivery system
TL;DR: The inhibition of prostate cancer cells (PC3 and DU145) viability from tubes encapsulating cisplatin proved the efficiency of the produced delivery system, and the development of CNTs as drug containers would pave the way to their employment as nanovectors into the cells.
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Macrophage-derived granulin drives resistance to immune checkpoint inhibition in metastatic pancreatic cancer
Valeria Quaranta,Carolyn Rainer,Sebastian R. Nielsen,Meirion Llŷr Raymant,Muhammad S Ahmed,Dannielle D. Engle,Arthur Taylor,Trish Murray,Fiona Campbell,Daniel H. Palmer,David A. Tuveson,Ainhoa Mielgo,Michael C. Schmid +12 more
TL;DR: It is found that macrophage-derived granulin contributes to cytotoxic CD8+ T-cell exclusion in metastatic livers, uncovering a mechanism by which metastatic PDAC tumors evade the immune response and providing the rationale for targeting granulin in combination with immune checkpoint inhibitors for the treatment of metastaticPDAC.
Non-invasive imaging reveals conditions that impact distribution and persistence of cells after in vivo administration
Lauren Scarfe,Arthur Taylor,Jack Sharkey,Rachel Harwood,Michael Barrow,Joan Comenge,Lydia Beeken,Cai Astley,Ilaria Santeramo,Claire Hutchinson,Lorenzo Ressel,Jon Smythe,Eric Austin,Raphaël Lévy,Matthew J. Rosseinsky,Dave J. Adams,Harish Poptani,Brian Kevin Park,Patricia Murray,Bettina Wilm +19 more
TL;DR: The observation that the hUC-MSCs but not the human bone marrow (hBM)-derived MSCs persisted for a period in some animals suggests that therapies with these cells should proceed with caution, and a thorough understanding of cell biodistribution and fate post administration is required.
Preventing Plasmon Coupling between Gold Nanorods Improves the Sensitivity of Photoacoustic Detection of Labeled Stem Cells in Vivo
Joan Comenge,Oihane Fragueiro,Jack Sharkey,Arthur Taylor,Marie Held,Neal C. Burton,Brian Kevin Park,Bettina Wilm,Patricia Murray,Mathias Brust,Raphaël Lévy +10 more
TL;DR: In this article, the steric hindrance provided by silica coating of the nanorods leads to the preservation of their spectral properties and improved photoacoustic sensitivity, which allowed the detection and monitoring of as few as 2 × 104 mesenchymal stem cells in mice over a period of 15 days with a high spatial resolution.
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