Arthur Krause
University Hospital of Basel
4 Papers
12 Citations
Arthur Krause is an academic researcher from University Hospital of Basel. The author has contributed to research in topics: Gene & Somatic evolution in cancer. The author has an hindex of 2, co-authored 4 publications.
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Papers
Activating mutations in the MAP-kinase pathway define non-ossifying fibroma of bone.
Daniel Baumhoer,Michal Kovac,Jan Sperveslage,Baptiste Ameline,Anna-Christina Strobl,Arthur Krause,Marcel Trautmann,Eva Wardelmann,Michaela Nathrath,Sylvia Höller,Jendrik Hardes,Georg Gosheger,Andreas H. Krieg,Volker Vieth,Roberto Tirabosco,Fernanda Amary,Adrienne M. Flanagan,Wolfgang Hartmann +17 more
TL;DR: This study adds another benign lesion to the spectrum of KRAS‐ and MAP‐kinase signalling‐driven tumours by identifying hotspot KRAS, FGFR1 and NF1 mutations in patients with non‐ossifying fibroma.
Deciphering the clonal relationship between glandular and squamous components in adenosquamous carcinoma of the lung using whole exome sequencing.
Arthur Krause,Luca Roma,Thomas Lorber,James M Habicht,Didier Lardinois,Maria R. De Filippo,Spasenija Savic Prince,Salvatore Piscuoglio,CharlotteKY Ng,Lukas Bubendorf +9 more
TL;DR: This first study using WES to elucidate the clonal evolution of ASC provides strong evidence that the LUAD and L USC components of ASC share a common origin and that theLUAD component appears to transform to LUSC.
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Exploring the spatiotemporal genetic heterogeneity in metastatic lung adenocarcinoma using a nuclei flow-sorting approach.
Thomas Lorber,Noemi Andor,Tanja Dietsche,Valeria Perrina,Darius Juskevicius,Karen Pereira,Stephanie U. Greer,Arthur Krause,David C Müller,Spasenija Savic Prince,Didier Lardinois,Michael T. Barrett,Christian Ruiz,Lukas Bubendorf +13 more
TL;DR: The results of this study provide evidence that most macroevolutionary events occur in primary tumors before metastatic dissemination and advocate for a limited degree of CIN over time and space in this cohort of LUADs.
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Genomic evolutionary trajectory of metastatic squamous cell carcinoma of the lung
Arthur Krause,Luca Roma,Thomas Lorber,Tanja Dietsche,Valeria Perrina,David C Müller,Didier Lardinois,Christian Ruiz,Spasenija Savic Prince,Salvatore Piscuoglio,Salvatore Piscuoglio,Charlotte K.Y. Ng,Lukas Bubendorf +12 more
TL;DR: In this paper, the authors defined the genomic landscape and evolutionary trajectories of metastatic squamous cell carcinoma of the lung (LUSC) combining nuclei-flow sorting and whole exome sequencing.