Arthur A. Patchett
United States Military Academy
18 Papers
61 Citations
Arthur A. Patchett is an academic researcher from United States Military Academy. The author has contributed to research in topics: Somatostatin & Angiotensin II. The author has an hindex of 4, co-authored 18 publications. Previous affiliations of Arthur A. Patchett include Merck & Co..
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Papers
Potent imidazole angiotensinII antagonists: acyl sulfonamides and acyl sulfamides as tetrazole replacements
Elizabeth M. Naylor,Prasun K. Chakravarty,Prasun K. Chakravarty,Colleen A. Costello,Colleen A. Costello,Raymond S.L. Chang,Raymond S.L. Chang,Tsing-Bau Chen,Tsing-Bau Chen,Kristie A. Faust,Kristie A. Faust,Victor J. Lotti,Victor J. Lotti,Salah D. Kivlighn,Salah D. Kivlighn,Gloria J. Zingaro,Gloria J. Zingaro,Peter K. S. Siegl,Peter K. S. Siegl,Pancras C. Wong,Pancras C. Wong,David J. Carini,David J. Carini,Ruth R. Wexler,Ruth R. Wexler,Arthur A. Patchett,Arthur A. Patchett,William J. Greenlee,William J. Greenlee +28 more
TL;DR: AT1 binding affinities for these potent AII antagonists were similar to their tetrazole analogs, and an enhancement in AT2 potencies was observed, particularly with acyl sulfonamides or sulfamides bearing hydrophobic substituents.
35
Patent
3-Hydroxy-3-aminoethyl beta -lactams
William J. Greenlee,Arthur A. Patchett +1 more
- 18 Mar 1986
20
Patent
Non-peptide somatostatin agonists
Liangqin Guo,Gregori J. Morriello,Yanping Pan,Alexander Pasternak,Arthur A. Patchett,Lihu Yang,Changyou Zhou +6 more
- 10 Jan 2001
TL;DR: In this article, non-peptide somatostatin agonist compounds of formula I wherein the substituents are as defined in claim 1 and the terms alkyl, aryl, heteroaryl, heterocyclyl and cycloalkyl have the specific meanings given in the specification.
6
Patent
Substituted quinazolinone having acidic functional group as angiotensin ii antagonist
Prasun K. Chakravarty,Laszlo Stephen E. De,Tomasz W. Glinka,William J. Greenlee,Dooseop Kim,Nathan B. Mantlo,Arthur A. Patchett,エー．パチェット アーサー,ジェー．グリーンリー ウイリアム,イー．デ ラズロ ステフェン,キム ドーセオプ,ダブリュ．グリンカ トマス,ビー．マントロ ナサン,ケー．チャクラヴァーティ プラサン +13 more
- 11 May 1992
TL;DR: In this paper, a new substd. quinazolinone having angiotensin II antagonistic action which is useful for treatment of hypertension and congestive failure was obtained.
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The Design of Peptidomimetic Growth Hormone Secretagogues
Arthur A. Patchett,Matthew J. Wyvratt +1 more
- 01 Jan 2000
TL;DR: A series of synthetic peptide analogs of Leu- and Met-enkephalins that specifically released growth hormone from the pituitary but possessed no opioid activity were reported in 1977, but this pioneering work was overshadowed a few years later by the discovery of an endogenous peptide hormone.
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