Arnold S. Lippa
New York University
11 Papers
207 Citations
Arnold S. Lippa is an academic researcher from New York University. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 3, co-authored 3 publications. Previous affiliations of Arnold S. Lippa include American Cyanamid.
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Papers
The Cholinergic Hypothesis of Geriatric Memory Dysfunction
Raymond T. Bartus,Raymond T. Bartus,Reginald L. Dean,Bernard Beer,Bernard Beer,Arnold S. Lippa,Arnold S. Lippa +6 more
TL;DR: Biochemical, electrophysiological, and pharmacological evidence supporting a role for cholinergic dysfunction in age-related memory disturbances is critically reviewed and an attempt has been made to identify pseudoissues, resolve certain controversies, and clarify misconceptions that have occurred in the literature.
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Animal tests of anxiety
TL;DR: This unit presents protocols for the most commonly used animal tests of anxiety, including the Geller‐Seifter conflict test, the social interaction test, light/dark exploration, the elevated plus‐maze, defensive burying, and the thirsty rat conflict.
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Animal Tests of Anxiety
TL;DR: This unit presents protocols for the most commonly used animal tests of anxiety, including the Geller‐Seifter conflict test, the social interaction test, light/dark exploration, the elevated plus‐maze, defensive burying, and the thirsty rat conflict.
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Hydrochloride Salt of the GABAkine KRM-II-81
Md. Yeunus Mian,Branka Divović,Dishary Sharmin,Kamal Prakash Pandey,Lalit K. Golani,Veera Venkata Naga Phani Babu Tiruveedhula,R. Cerne,Jodi L. Smith,Xingjie Ping,Xiaoming Jin,Gregory H. Imler,Jeffrey R. Deschamps,Arnold S. Lippa,James M. Cook,Miroslav M. Savić,James M. Rowlett,Jeffrey M. Witkin +16 more
TL;DR: In this article , a hydrochloride salt of KRM-II-81 was prepared from the free base with anhydrous hydrochloric acid, which was confirmed by X-ray crystallography, as well as 1H NMR and 13C NMR analyses.
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Structural analogs of the GABAkine (5-(8-ethynyl-6-(pyridin-2-yl)-4H-benzo[ f ]imidazole[1,5-α ] [1,4]diazepin-3-yl) oxazole) (KRM-II-81) are orally bioavailable anticonvulsants without sedation1.
K. P. Pandey,Branka Divović,Farjana Rashid,Lalit K. Golani,R. Cerne,Nicolas M Zahn,Michelle J. Meyer,Alexander Leggy Arnold,Dishary Sharmin,Md. Yeunus Mian,Jodi L Smith,Xingjie Ping,Xiaoming Jin,Arnold S. Lippa,Veera Venkata Naga Phani Babu Tiruveedhula,James M. Cook,Miroslav M. Savić,Jeffrey M. Witkin +17 more
TL;DR: In this paper , three back-up compounds to support the development of the GABAA receptor (GABAAR) potentiator, KRM-II-81, were designed.
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