Arnold M. Falick
University of California, Berkeley
66 Papers
808 Citations
Arnold M. Falick is an academic researcher from University of California, Berkeley. The author has contributed to research in topics: Mass spectrometry & Peptide sequence. The author has an hindex of 33, co-authored 66 publications. Previous affiliations of Arnold M. Falick include Applied Biosystems & University of California, San Francisco.
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Papers
The Ste5 Scaffold Allosterically Modulates Signaling Output of the Yeast Mating Pathway
Roby P. Bhattacharyya,Attila Reményi,Matthew C. Good,Caleb J. Bashor,Arnold M. Falick,Wendell A. Lim +5 more
TL;DR: It is found that the Ste5 scaffold has a more active role in the yeast mating pathway: A fragment of Ste5 allosterically activated autophosphorylation of the mitogen-activated protein kinase Fus3 appears to have a negative regulatory role.
307
Structure of Mycobacterium tuberculosis PknB supports a universal activation mechanism for Ser/Thr protein kinases.
TL;DR: The structural and chemical similarities of PknB to metazoan homologs support a universal activation mechanism of Ser/Thr protein kinases in prokaryotes and eukaryotes.
237
N-terminal processing of proteins exported by malaria parasites
Henry H. Chang,Arnold M. Falick,Peter M. Carlton,John W. Sedat,Joseph L. DeRisi,Joseph L. DeRisi,Michael A. Marletta +6 more
TL;DR: It was shown that the recognition of the processed N-terminus of exported proteins within the parasitophorous vacuole may be crucial for protein transport to the host erythrocyte.
204
Isolation of a U‐insertion/deletion editing complex from Leishmania tarentolae mitochondria
Ruslan Aphasizhev,Inna Aphasizheva,R.E. Nelson,Guanghan Gao,Agda M. Simpson,Xuedong Kang,Arnold M. Falick,Sandro Sbicego,Larry Simpson +8 more
TL;DR: A multiprotein, high molecular weight complex active in both U‐insertion and U‐deletion as judged by a pre‐cleaved RNA editing assay was isolated from mitochondrial extracts of Leishmania tarentolae by the tandem affinity purification (TAP) procedure, using three different TAP‐tagged proteins of the complex.
Guide RNA-binding complex from mitochondria of trypanosomatids.
James Weng,Inna Aphasizheva,Ronald D. Etheridge,Lan Huang,Xiaorong Wang,Arnold M. Falick,Ruslan Aphasizhev +6 more
TL;DR: Systematic analysis of RNA-mediated and RNA-independent interactions involving the GRBC and MERS1 suggests a unified model for RNA processing in the kinetoplast mitochondria.
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