Arnaud Droit
Laval University
197 Papers
368 Citations
Arnaud Droit is an academic researcher from Laval University. The author has contributed to research in topics: Biology & Medicine. The author has an hindex of 29, co-authored 143 publications. Previous affiliations of Arnaud Droit include University of Washington & University of Alberta.
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Papers
Fast and accurate bacterial species identification in biological samples using LC-MS/MS mass spectrometry and machine learning
Florence Roux-Dalvai,Clarisse Gotti,Mickael Leclercq,Marie-Claude Hélie,Maurice Boissinot,Tabiwang N. Arrey,Claire Dauly,Frédéric Fournier,Isabelle Kelly,Judith Marcoux,Julie Bestman-Smith,Michel G. Bergeron,Arnaud Droit +12 more
TL;DR: The efficiency of this method for the rapid and specific identification of the bacterial species causing UTI and could be extended in the future to other biological specimens and to bacteria having specific virulence or resistance factors.
Case Report: Two Families With HPDL Related Neurodegeneration
Ieva Micule,Baiba Lace,Nathan T. Wright,Nicolas Chrestian,Jurgis Strautmanis,Mikus Diriks,Janis Stavusis,D. Kidere,Elfa Kleina,Anna Ždanoviča,Nataly Laflamme,N. Rioux,Samarth Thonta Setty,Sander Pajusalu,Arnaud Droit,Monkol Lek,Serge Rivest,Inna Inashkina +17 more
TL;DR: Two probands from unrelated families presenting with severe and intermediate variations of the clinical course are reported, with a homozygous variant in the HPDL gene detected in each proband; however, there was no known parental consanguinity.
Lipid metabolic reprogramming of hepatic CD4+ T cells during SIV infection
Julien Clain,Steven Boutrais,Juliette Dewatines,Gina Racine,Henintsoa Rabezanahary,Arnaud Droit,Ouafa Zghidi-Abouzid,Jérôme Estaquier +7 more
TL;DR: The model of simian immunodeficiency virus (SIV)-infected rhesus macaques to access liver tissue demonstrated that hepatic CD4+ T cells express CCR5, the main viral coreceptor, and are infected, and activated CD4- T cells are reprogrammed toward lipid metabolism after SIV infection.
Fine scale mapping of the 17q22 breast cancer locus using dense SNPs, genotyped within the Collaborative Oncological Gene-Environment Study (COGs)
Hatef Darabi,Jonathan Beesley,Arnaud Droit,Siddhartha Kar,Silje Nord,Mahdi Moradi Marjaneh,Penny Soucy,Kyriaki Michailidou,Kyriaki Michailidou,Maya Ghoussaini,Hanna Fues Wahl,Manjeet K. Bolla,Qin Wang,Joe Dennis,M. Rosario Alonso,Irene L. Andrulis,Hoda Anton-Culver,Volker Arndt,Matthias W. Beckmann,Javier Benitez,Natalia Bogdanova,Stig E. Bojesen,Hiltrud Brauch,Hiltrud Brauch,Hiltrud Brauch,Hermann Brenner,Annegien Broeks,Thomas Brüning,Barbara Burwinkel,Barbara Burwinkel,Jenny Chang-Claude,Jenny Chang-Claude,Ji Yeob Choi,Don M. Conroy,Fergus J. Couch,Angela Cox,Simon S. Cross,Kamila Czene,Peter Devilee,Thilo Dörk,Douglas F. Easton,Peter A. Fasching,Peter A. Fasching,Jonine Figueroa,Jonine Figueroa,Olivia Fletcher,Henrik Flyger,Eva Galle,Montserrat Garcia-Closas,Graham G. Giles,Graham G. Giles,Mark S. Goldberg,Anna González-Neira,Pascal Guénel,Christopher A. Haiman,Emily Hallberg,Ute Hamann,Mikael Hartman,Antoinette Hollestelle,John L. Hopper,Hidemi Ito,Anna Jakubowska,Nichola Johnson,Daehee Kang,Sofia Khan,Veli-Matti Kosma,Mieke Kriege,Vessela N. Kristensen,Diether Lambrechts,Loic Le Marchand,Soo-Chin Lee,Annika Lindblom,Artitaya Lophatananon,Jan Lubinski,Arto Mannermaa,Siranoush Manoukian,Sara Margolin,Keitaro Matsuo,Rebecca Mayes,James McKay,Alfons Meindl,Roger L. Milne,Roger L. Milne,Kenneth Muir,Kenneth Muir,Susan L. Neuhausen,Heli Nevanlinna,Curtis Olswold,Nick Orr,Paolo Peterlongo,Guillermo Pita,Katri Pylkäs,Anja Rudolph,Suleeporn Sangrajrang,Elinor J. Sawyer,Marjanka K. Schmidt,Rita K. Schmutzler,Caroline Seynaeve,Mitul Shah,Chen-Yang Shen,Xiao-Ou Shu,Melissa C. Southey,Daniel O. Stram,Harald Surowy,Harald Surowy,Anthony J. Swerdlow,Soo Hwang Teo,Daniel C. Tessier,Ian Tomlinson,Diana Torres,Diana Torres,Thérèse Truong,Celine M. Vachon,Daniel Vincent,Robert Winqvist,Anna H. Wu,Pei-Ei Wu,Cheng Har Yip,Wei Zheng,Paul D.P. Pharoah,Per Hall,Stacey L. Edwards,Jacques Simard,Juliet D. French,Georgia Chenevix-Trench,Alison M. Dunning +125 more
TL;DR: High resolution fine-mapping analysis identified 28 highly correlated common variants, in a 53 Kb region spanning two introns of the STXBP4 gene, that are strong candidates for driving breast cancer risk and are correlated with two previously reported risk-associated variants at this locus.
Quality assessment of peptide tandem mass spectra
TL;DR: A novel method to assess the quality of tandem mass spectra is developed, which can eliminate majority of poor quality spectra while losing very minority of highquality spectra.