Arindam Paul
University of Kansas
10 Papers
Arindam Paul is an academic researcher from University of Kansas. The author has contributed to research in topics: Cancer & Embryonic stem cell. The author has an hindex of 8, co-authored 10 publications.
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Papers
Inhibition of Protein Kinase C Signaling Maintains Rat Embryonic Stem Cell Pluripotency
Ganeshkumar Rajendran,Debasree Dutta,James Hong,Arindam Paul,Biswarup Saha,Biraj Mahato,Soma Ray,Pratik Home,Avishek Ganguly,Mark L. Weiss,Soumen Paul +10 more
TL;DR: It is shown that inhibition of PKC signaling is an efficient strategy to establish and maintain pluripotent rESCs and to facilitate reprogramming of rat embryonic fibroblasts to rat induced pluripotency stem cells.
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PKCλ/ι signaling promotes triple-negative breast cancer growth and metastasis
Arindam Paul,Sumedha Gunewardena,Shane R. Stecklein,Biswarup Saha,Nikhil K. Parelkar,Marsha Danley,Ganeshkumar Rajendran,Pratik Home,Soma Ray,Iman Jokar,George A. Vielhauer,Roy A. Jensen,Ossama Tawfik,Soumen Paul +13 more
TL;DR: It is reported that expression of atypical protein kinase C isoform, PKCλ/ι, significantly increased and activated in all invasive breast cancer (invasive ductal carcinoma or IDC) subtypes including the TNBC subtype, and induction and activation of PKC ε promote TNBC growth, invasion and metastasis.
PKCλ/ι signaling-a common node for normal cellular development and breast oncogenesis.
Arindam Paul,Soumen Paul +1 more
TL;DR: This commentary highlights some key functions of PKCλ/ι signaling that are integral to both normal development and cancer progression.
Breast Cancer Invasion and Metastasis
Shane R. Stecklein,Hanan S. Elsarraj,Kelli E. Valdez,Arindam Paul,Fariba Behbod +4 more
- 01 Jan 2013
TL;DR: This chapter discusses the morphologic and molecular heterogeneity of breast cancer and the relationship between breast cancer subtype and metastatic potential, and addresses the strengths and shortcomings of different in vivo models that allow integrated analysis of heterotypic signaling and tissue architecture in breast cancer progression.
Genetic redundancy of GATA factors in the extraembryonic trophoblast lineage ensures the progression of preimplantation and postimplantation mammalian development.
Pratik Home,Ram Parikshan Kumar,Avishek Ganguly,Biswarup Saha,Jessica Milano-Foster,Bhaswati Bhattacharya,Soma Ray,Sumedha Gunewardena,Arindam Paul,Sally A. Camper,Patrick E. Fields,Soumen Paul +11 more
TL;DR: It is shown that genetic redundancy of Gata3 with paralog Gata2 in trophoblast progenitors ensures the successful progression of both pre- and postimplantation mammalian development.