Antonios Margaritis
University of Siena
10 Papers
37 Citations
Antonios Margaritis is an academic researcher from University of Siena. The author has contributed to research in topics: Cysteine & Homocysteine. The author has an hindex of 7, co-authored 9 publications.
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Papers
Protein-thiol substitution or protein dethiolation by thiol/disulfide exchange reactions: the albumin model.
Domenico Summa,Ottavia Spiga,Andrea Bernini,Vincenzo Venditti,Raffaella Priora,Simona Frosali,Antonios Margaritis,Danila Di Giuseppe,Neri Niccolai,Paolo Di Simplicio +9 more
TL;DR: Structures by molecular simulation of thiolated albumin evidenced that the sulfur exposure in mixed disulfide process is important for the rate but not for determining the kind of reaction (substitution or dethiolation).
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Regulation of redox forms of plasma thiols by albumin in multiple sclerosis after fasting and methionine loading test
Danila Di Giuseppe,Monica Ulivelli,Sabina Bartalini,Stefania Battistini,Alfonso Cerase,Stefano Passero,Domenico Summa,Simona Frosali,Raffaella Priora,Antonios Margaritis,Paolo Di Simplicio +10 more
TL;DR: It is demonstrated that albumin-dependent SH/SS exchange reactions are a potent regulation system of thiol redox species in plasma and a useful in vivo test to assay the functionality of the methionine cycle and transsulfuration reactions.
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The role of protein sulfhydryl groups and protein disulfides of the platelet surface in aggregation processes involving thiol exchange reactions.
Antonios Margaritis,Raffaella Priora,Simona Frosali,Danila Di Giuseppe,Domenico Summa,Lucia Coppo,Anna Di Stefano,Paolo Di Simplicio +7 more
TL;DR: The data strongly suggest that the PSH blockage and the PSSP reduction of the platelet surface are deeply involved in aggregation processes evoked in protein rich plasma and washed platelets by ADP and collagen.
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Administration of Minor Polar Compound-Enriched Extra Virgin Olive Oil Decreases Platelet Aggregation and the Plasma Concentration of Reduced Homocysteine in Rats
Raffaella Priora,Domenico Summa,Simona Frosali,Antonios Margaritis,Danila Di Giuseppe,Chiara Lapucci,Francesca Ieri,Fabio M. Pulcinelli,Annalisa Romani,Flavia Franconi,Paolo Di Simplicio +10 more
TL;DR: Results show that MPC in EVOO inhibit platelet aggregation and reduce the plasma rHcy concentration, effects that may be associated with cardiovascular protection.
The control of S-thiolation by cysteine via gamma-glutamyltranspeptidase and thiol exchanges in erythrocytes and plasma of diamide-treated rats
Raffaella Priora,Lucia Coppo,Antonios Margaritis,Danila Di Giuseppe,Simona Frosali,Domenico Summa,Jongyun Heo,Paolo Di Simplicio +7 more
TL;DR: There were indications from in vitro experiments that the CSSP accumulation in erythrocytes of diamide-treated rats derives from the coexistence of GSH hydrolysis via gamma-GT and production of reduced cysteine via plasma thiol exchanges, and reduced Cysteine was found to be involved in deglutathionylation processes.
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