Antonio Basile
University of Bari
11 Papers
19 Citations
Antonio Basile is an academic researcher from University of Bari. The author has contributed to research in topics: Angiogenesis & Bone marrow. The author has an hindex of 8, co-authored 11 publications.
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Papers
Bone marrow fibroblasts parallel multiple myeloma progression in patients and mice: in vitro and in vivo studies
Maria Antonia Frassanito,Luigia Rao,Michele Moschetta,Roberto Ria,L. Di Marzo,A De Luisi,Vito Racanelli,Ivana Catacchio,Simona Berardi,Antonio Basile,Eline Menu,Simona Ruggieri,Beatrice Nico,Domenico Ribatti,Ruggiero Fumarulo,F. Dammacco,Karin Vanderkerken,Angelo Vacca +17 more
TL;DR: Cytofluorimetric analysis revealed higher proportions of bone marrow CAFs in patients with active MM (both at diagnosis and relapse) compared with patients in remission or those with monoclonal gammopathy of undetermined significance or deficiency anemia (controls).
Epha3 acts as proangiogenic factor in multiple myeloma
Antonella Caivano,Francesco La Rocca,Ilaria Laurenzana,Tiziana Annese,Roberto Tamma,Ubaldo Famigliari,Vittorio Simeon,Stefania Trino,Luciana De Luca,Oreste Villani,Simona Berardi,Antonio Basile,Angelo Vacca,Giuseppe Saglio,Luigi Del Vecchio,Pellegrino Musto,Daniela Cilloni +16 more
TL;DR: It is found that EphA3 is highly expressed in MMECs compared to the other EC types, and gene expression profiling showed that knockdown of E phA3 down modulated some molecules that regulate adhesion, migration and invasion processes.
Bone marrow vascular niche and the control of angiogenesis in multiple myeloma.
TL;DR: The mechanisms involved in the generation of signals released by endothelial cells in the "vascular niche" that promote tumor growth in multiple myeloma are described.
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Hypoxia-Inducible Factor-1 in Multiple Myeloma Progression.
Roberto Ria,Antonia Reale,Simona Berardi,Claudia Piccoli,Giulia Di Pietro,Antonio Basile,Nazareno Capitanio,Angelo Vacca +7 more
TL;DR: The findings indicate that HIF-1a plays an important role in MM progression and that it is correlated to the angiogenic switch from nonactive MM to active MM, and suggest that Hif- 1a may represent a target for the MM antiangiogenic treatment.
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EphA3 As a Molecular Target In Multiple Myeloma: Opportunity For a Novel Therapeutic Approach With a Specific Monoclonal Antibody
Antonella Caivano,Francesco La Rocca,Ilaria Laurenzana,Alessandra Favole,Irma Airoldi,Emma Di Carlo,Valentina Gaidano,Enrico Bracco,Oreste Villani,Giuseppe Pietrantuono,Luciana De Luca,Annalisa Morano,Vittorio Simeon,Stefania Trino,Simona Berardi,Antonio Basile,Martin Lackmann,Angelo Vacca,Pellegrino Musto,Francesco Frassoni,Daniela Cilloni +20 more
TL;DR: The EphA3 role in MM patients was investigated in order to define whether it may represent a potential new molecular target for a novel therapeutic approach with a specific anti Eph a3 monoclonal antibody.
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