Antonia Post
University of Würzburg
14 Papers
71 Citations
Antonia Post is an academic researcher from University of Würzburg. The author has contributed to research in topics: Gene & Signal transduction. The author has an hindex of 10, co-authored 14 publications. Previous affiliations of Antonia Post include Goethe University Frankfurt.
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Papers
Interaction of brain 5-HT synthesis deficiency, chronic stress and sex differentially impact emotional behavior in Tph2 knockout mice
Lise Gutknecht,Lise Gutknecht,Sandy Popp,Jonas Waider,Frank M. J. Sommerlandt,Corinna Göppner,Antonia Post,Andreas Reif,Daniel L.A. van den Hove,Tatyana Strekalova,Angelika Schmitt,Maria B. N. Colaςo,Claudia Sommer,Rupert Palme,Klaus-Peter Lesch,Klaus-Peter Lesch +15 more
TL;DR: The results indicate that 5-HT mediates behavioral responses to environmental adversity by facilitating the encoding of stress effects leading to increased vulnerability for negative emotionality.
OCD-like behavior is caused by dysfunction of thalamo-amygdala circuits and upregulated TrkB/ERK-MAPK signaling as a result of SPRED2 deficiency
M Ullrich,M Weber,Antonia Post,Antonia Post,Sandy Popp,J Grein,M Zechner,H Guerrero González,A Kreis,Angelika Schmitt,Nurcan Üçeyler,K-P Lesch,K-P Lesch,Kai Schuh +13 more
TL;DR: This study identifies SPRED2 as a promising new regulator, TrkB/ERK-MAPK signaling as a novel mediating mechanism, and thalamo-amygdala synapses as critical circuitry involved in the pathogenesis of OCD.
Experimental heart failure causes depression-like behavior together with differential regulation of inflammatory and structural genes in the brain
Anna Frey,Sandy Popp,Antonia Post,Simon Langer,Marc Lehmann,Ulrich Hofmann,Anna-Leena Sirén,Leif Hommers,Angelika Schmitt,Tatyana Strekalova,Georg Ertl,Klaus-Peter Lesch,Klaus-Peter Lesch,Stefan Frantz +13 more
TL;DR: After induction of ischemic CHF, mice exhibited anhedonic behavior, decreased exploratory activity and interest in novelty, and cognitive impairment analogous to symptoms observed in humans with CHF and comorbid depression.
Gene-environment interaction influences anxiety-like behavior in ethologically based mouse models.
Antonia Post,Peter Weyers,Peter Holzer,Evelin Painsipp,Paul Pauli,Thomas Wultsch,Andreas Reif,Klaus-Peter Lesch +7 more
TL;DR: A novel method based on infrared lighting from below, coupled to respective video-tracking equipment, which facilitates standard testing of behavior interference-free in complete darkness and challenges the comparability of not sufficiently standardized tests of anxiety-like behavior.
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The genetic contribution of the NO system at the glutamatergic post-synapse to schizophrenia: further evidence and meta-analysis.
Heike Weber,Daniel Klamer,Florian Freudenberg,Sarah Kittel-Schneider,Olga Rivero,Olga Rivero,Claus-Jürgen Scholz,Julia Volkert,Juliane Kopf,Julia Heupel,Sabine Herterich,Rolf Adolfsson,A. Alttoa,Antonia Post,H. Grußendorf,A. Kramer,Alexandra Gessner,Boris Schmidt,Susanne Hempel,Christian Jacob,Julio Sanjuán,María Dolores Moltó,Klaus-Peter Lesch,Christine M. Freitag,Lindsey Kent,Andreas Reif +25 more
TL;DR: The data argue that genetic variance in NOS1 resulting in lower prefrontal brain expression of this gene contributes to schizophrenia liability, and that Nos1 interacts with NOS2AP in doing so, and the NOS 1-NOS1AP PDZ interface may thus well constitute a novel target for small molecules in at least some forms of schizophrenia.
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