Antoine Gessain
Pasteur Institute
472 Papers
5.8K Citations
Antoine Gessain is an academic researcher from Pasteur Institute. The author has contributed to research in topics: Virus & Population. The author has an hindex of 70, co-authored 451 publications. Previous affiliations of Antoine Gessain include Centre national de la recherche scientifique & National Institutes of Health.
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Papers
Antibodies to human t-lymphotropic virus type-i in patients with tropical spastic paraparesis
TL;DR: Findings suggest either that HTLV-I is neurotropic or that the virus or a related one contributes to the pathogenesis of TSP.
2.8K
Epidemiological Aspects and World Distribution of HTLV-1 Infection
TL;DR: The human T-cell leukemia virus type 1 (HTLV-1), identified as the first human oncogenic retrovirus 30 years ago, is not an ubiquitous virus, with clusters of high endemicity located often nearby areas where the virus is nearly absent.
Meta-Analysis on the Use of Zidovudine and Interferon-Alfa in Adult T-Cell Leukemia/Lymphoma Showing Improved Survival in the Leukemic Subtypes
Ali Bazarbachi,Yves Plumelle,Juan Carlos Ramos,Patricia Tortevoye,Zaher K. Otrock,Graham P. Taylor,Antoine Gessain,William J. Harrington,Gérard Panelatti,Olivier Hermine +9 more
TL;DR: A meta-analysis of antiviral therapy of ATL confirmed the high efficacy of AZT and IFN, which should now be considered the gold standard first-line therapy in leukemic subtypes of ATL.
362
Biofilm-like extracellular viral assemblies mediate HTLV-1 cell-to-cell transmission at virological synapses
Ana-Monica Pais-Correia,Martin Sachse,Stéphanie Guadagnini,Valentina Robbiati,Rémi Lasserre,Antoine Gessain,Olivier Gout,Andres Alcover,Maria-Isabel Thoulouze +8 more
TL;DR: It is shown that HTLV-1–infected T lymphocytes transiently store viral particles as carbohydrate-rich extracellular assemblies that are held together and attached to the cell surface by virally-inducedextracellular matrix components, including collagen and agrin, and cellular linker proteins, such as tetherin and galectin-3.
326
Human herpesvirus 8 transmission from mother to child and between siblings in an endemic population
Sabine Plancoulaine,Sabine Plancoulaine,Laurent Abel,Laurent Abel,Monique van Beveren,David-Alexandre Trégouët,Michel Joubert,Patricia Tortevoye,Antoine Gessain +8 more
TL;DR: This pattern of familial aggregation, together with the variation of HHV-8 seroprevalence with age, indicate that, in endemic populations, HHv-8 transmission mainly occurs from mother to child and between siblings during childhood and adolescence.
295