Antoine Drieu

TL;DR: The timing of the stroke immune pathophysiology, the immune responses to stroke sift-through cell type, and the pitfalls on the translation from experimental studies to clinical trials testing the therapeutic pertinence of immune modulators are described.

TL;DR: Transgenic mice are developed and results indicate that ACE points are a critical part of the anatomy of neuroimmune communication in both mice and humans that link the central nervous system with the dura and its immunological diversity and waste clearance systems.

TL;DR: It is demonstrated that neural networks synchronize individual action potentials to create large-amplitude, rhythmic and self-perpetuating ionic waves in the interstitial fluid of the brain, demonstrating that neurons serve as master organizers for brain clearance.

TL;DR: The tPA present in the blood circulation is capable of potentiating the cerebral blood flow increase induced by the activation of the mouse somatosensorial cortex, and that this effect is mediated by a tPA-dependent activation of NMDAR expressed at the luminal part of endothelial cells of arteries.