Antoaneta Mincheva
German Cancer Research Center
36 Papers
371 Citations
Antoaneta Mincheva is an academic researcher from German Cancer Research Center. The author has contributed to research in topics: Gene & Exon. The author has an hindex of 20, co-authored 36 publications.
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Papers
Molecular characterization of a slowly gating human hyperpolarization-activated channel predominantly expressed in thalamus, heart, and testis
Reinhard Seifert,Alexander Scholten,Renate Gauss,Antoaneta Mincheva,Peter Lichter,U. Benjamin Kaupp +5 more
TL;DR: The characteristic expression pattern and the sluggish gating suggest that hHCN4 controls the rhythmic activity in both thalamocortical neurons and pacemaker cells of the heart.
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Adrenocortical carcinoma is characterized by a high frequency of chromosomal gains and high-level amplifications.
Martha Dohna,Martin Reincke,Antoaneta Mincheva,Bruno Allolio,Sabina Solinas-Toldo,Peter Lichter +5 more
TL;DR: Interestingly, the adenomas larger than 4 cm contained gained material of regions also overrepresented in carcinomas, indicating that the larger adrenal lesions need to be carefully considered in the diagnosis of adrenocortical tumors, and that genetic aberrations might provide useful markers for a better diagnostic differentiation.
171
Comprehensive genomic analysis of desmoplastic medulloblastomas: identification of novel amplified genes and separate evaluation of the different histological components.
Antje Ehrbrecht,U. Müller,Marietta Wolter,Alexander Hoischen,Arend Koch,Bernhard Radlwimmer,Bertrand Actor,Antoaneta Mincheva,Thorsten Pietsch,Peter Lichter,Guido Reifenberger,Ruthild G. Weber +11 more
TL;DR: Several novel genetic alterations in DMBs are identified and genetic evidence for a monoclonal origin of their different tissue components is provided, and common chromosomal imbalances in five of six informative tumours are identified.
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Pbx4, a new Pbx family member on mouse chromosome 8, is expressed during spermatogenesis.
TL;DR: Members of the Pbx family are involved in a diverse range of developmental processes including axial patterning and organogenesis, and expression is confined to the testis, especially to spermatocytes in the first meiotic prophase.
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Transcriptional and translational downregulation of H-REV107 , a class II tumour suppressor gene located on human chromosome 11q11-12
Knut Husmann,Christine Sers,Christine Sers,Ellen Fietze,Antoaneta Mincheva,Peter Lichter,Reinhold Schäfer,Reinhold Schäfer +7 more
TL;DR: The H-rev107 tumour suppressor was isolated as a gene specifically expressed in rat fibroblasts resistant toward malignant transformation by the activated HRAS gene and the predicted rat and human proteins are highly conserved exhibiting an overall amino acid identity of 83%.
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