Annemieke Verstuyf
Katholieke Universiteit Leuven
165 Papers
1.5K Citations
Annemieke Verstuyf is an academic researcher from Katholieke Universiteit Leuven. The author has contributed to research in topics: Calcitriol receptor & Vitamin D and neurology. The author has an hindex of 44, co-authored 153 publications. Previous affiliations of Annemieke Verstuyf include Catholic University of Leuven & The Catholic University of America.
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Papers
Vitamin D: Metabolism, Molecular Mechanism of Action, and Pleiotropic Effects.
TL;DR: The structure of the liganded VDR/RXR complex was recently characterized using cryoelectron microscopy, X-ray scattering, and hydrogen deuterium exchange, which will result in a more complete understanding of VDR coactivator interactions, thus facilitating cell and gene specific clinical applications.
Vitamin D and cancer.
TL;DR: The antiproliferative action makes 1,25-(OH)(2)D and its analogs a possible therapeutic tool to treat hyperproliferative disorders, among which different types of cancer.
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Vitamin D's Effect on Immune Function.
TL;DR: In this review, the attention is shifted towards the importance of the extra-skeletal effects of vitamin D, with special emphasis on the immune system.
The vitamin D receptor gene FokI polymorphism: functional impact on the immune system.
Evelyne van Etten,Lieve Verlinden,Annapaula Giulietti,Elizabeth Ramos-Lopez,Dumitru Branisteanu,Gabriela B Ferreira,Lutgart Overbergh,Annemieke Verstuyf,Roger Bouillon,Bart O. Roep,Klaus Badenhoop,Chantal Mathieu +11 more
TL;DR: Data provide the first evidence that the VDR FokI polymorphism affects immune cell behavior, with a more active immune system for the short F‐VDR, thus possibly playing a role in immune‐mediated diseases.
258
Vitamin D3 Induces Tolerance in Human Dendritic Cells by Activation of Intracellular Metabolic Pathways.
Gabriela B Ferreira,An-Sofie Vanherwegen,Guy Eelen,Ana Carolina Elisa Fierro Gutiérrez,Leentje Van Lommel,Kathleen Marchal,Kathleen Marchal,Lieve Verlinden,Annemieke Verstuyf,Tatiane C Nogueira,Maria Georgiadou,Frans Schuit,Decio L. Eizirik,Conny Gysemans,Peter Carmeliet,Lut Overbergh,Chantal Mathieu +16 more
TL;DR: It is put forward that these metabolic insights in tolerogenic DC biology can be used to advance DC-based immunotherapies, influencing DC longevity and their resistance to environmental metabolic stress.
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